Segment Information - Schedule of Reportable Segment Profit and Loss, Including Significant Expense Categories, Attributable to the Company's Reportable Segment (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Revenues [Abstract]
Total revenue	$ 37,314	$ 371,206	$ 1,198
Operating Expenses [Abstract]
Research and development expense	320,653	387,332	461,645
General and administrative expense	72,977	76,162	102,464
Collaboration expense, net	110,250	130,250	110,250
Stock-based compensation expense	86,567	81,028	97,947
Depreciation expense	19,200	19,800	24,100
Other income, net	103,901	71,816	22,661
Provision (benefit) for income taxes	3,587	2,888	(325)
Segment net income	(366,252)	(153,610)	(650,175)
Net loss	(366,252)	(153,610)	(650,175)
Operating Segments [Member]
Operating Expenses [Abstract]
Research and development expense	262,427	330,121	397,067
General and administrative expense	25,453	32,589	45,012
Collaboration expense, net	110,250	130,250	110,250
Stock-based compensation expense	86,567	81,028	97,947
Depreciation expense	19,183	19,756	24,083
Other income, net	(103,901)	(71,816)	(22,661)
Provision (benefit) for income taxes	3,587	2,888	(325)
Segment net income	(366,252)	(153,610)	(650,175)
Adjustments or reconciling items	0	0	0
Net loss	(366,252)	(153,610)	(650,175)
Collaboration Revenue [Member]
Revenues [Abstract]
Total revenue	35,000	370,000	436
Collaboration Revenue [Member] | Operating Segments [Member]
Revenues [Abstract]
Total revenue	35,000	370,000	436
Grant Revenue [Member]
Revenues [Abstract]
Total revenue	2,314	1,206	762
Grant Revenue [Member] | Operating Segments [Member]
Revenues [Abstract]
Total revenue	$ 2,314	$ 1,206	$ 762