Accrued Expenses - Schedule of Accrued Expenses (Detail) - USD ($) $ in Thousands	Dec. 31, 2024	Dec. 31, 2023
Accrued Liabilities, Current [Abstract]
Payroll and employee-related costs	$ 18,443	$ 17,347
Research costs	15,549	16,962
Collaboration costs	0	2,395
Licensing fees	1,850	3,143
Professional fees	3,086	2,515
Intellectual property costs	1,513	1,642
Accrued property and equipment	151	630
Other	480	701
Total	$ 41,072	$ 45,335