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Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Sep. 30, 2024
Sep. 30, 2023
Revenue:        
Total revenue $ 602 $ 0 $ 1,623 $ 170,000
Operating expenses:        
Research and development 82,160 90,698 238,498 292,188
General and administrative 17,419 18,291 54,853 59,683
Collaboration expense, net 11,153 23,422 110,250 110,250
Total operating expenses 110,732 132,411 403,601 462,121
Loss from operations (110,130) (132,411) (401,978) (292,121)
Other income:        
Other income, net 25,064 20,671 75,924 51,819
Total other income, net 25,064 20,671 75,924 51,819
Net loss before income taxes (85,066) (111,740) (326,054) (240,302)
Provision for income taxes (876) (412) (2,887) (2,655)
Net loss (85,942) (112,152) (328,941) (242,957)
Foreign currency translation adjustment 76 (49) 66 12
Unrealized gain on marketable securities 13,368 2,160 8,586 8,838
Comprehensive loss $ (72,498) $ (110,041) $ (320,289) $ (234,107)
Net loss per common share - basic $ (1.01) $ (1.41) $ (3.92) $ (3.07)
Basic weighted-average common shares outstanding 85,234,926 79,414,098 83,988,063 79,063,415
Net loss per common share - diluted $ (1.01) $ (1.41) $ (3.92) $ (3.07)
Diluted weighted-average common shares outstanding 85,234,926 79,414,098 83,988,063 79,063,415
Collaboration Revenue [Member]        
Revenue:        
Total revenue $ 0 $ 0 $ 0 $ 170,000
Grant Revenue [Member]        
Revenue:        
Total revenue $ 602 $ 0 $ 1,623 $ 0