Consolidated Statements of Operations and Comprehensive (Loss) Income - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
Revenue:
Total revenue	$ 371,206	$ 1,198	$ 914,963
Operating expenses:
Research and development	387,332	461,645	340,567
General and administrative	76,162	102,464	99,690
Collaboration expense, net	130,250	110,250	101,178
Total operating expenses	593,744	674,359	541,435
(Loss) income from operations	(222,538)	(673,161)	373,528
Other income
Other income, net	71,816	22,661	6,003
Total other income, net	71,816	22,661	6,003
Net income (loss) before income taxes	(150,722)	(650,500)	379,531
(Provision) benefit for income taxes	(2,888)	325	(1,870)
Net (loss) income	(153,610)	(650,175)	377,661
Foreign currency translation adjustment	73	(80)	(11)
Unrealized gain (loss) on marketable securities	17,487	(10,500)	(4,973)
Comprehensive (loss) income	$ (136,050)	$ (660,755)	$ 372,677
Net (loss) income per common share - basic	$ (1.94)	$ (8.36)	$ 4.97
Basic weighted-average common shares outstanding	79,220,930	77,746,575	75,948,686
Net (loss) income per common share - diluted	$ (1.94)	$ (8.36)	$ 4.7
Diluted weighted-average common shares outstanding	79,220,930	77,746,575	80,393,496
Collaboration Revenue [Member]
Revenue:
Total revenue	$ 370,000	$ 436	$ 913,081
Grant Revenue [Member]
Revenue:
Total revenue	$ 1,206	$ 762	$ 1,882