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Document and Entity Information - USD ($)
$ in Billions
 12 Months Ended
Dec. 31, 2023
Feb. 16, 2024
Jun. 30, 2023
Cover [Abstract]      
Document Type 10-K    
Amendment Flag false    
Document Period End Date Dec. 31, 2023    
Document Fiscal Year Focus 2023    
Document Fiscal Period Focus FY    
Title of 12(b) Security Common Shares, nominal value CHF 0.03    
Trading Symbol CRSP    
Security Exchange Name NASDAQ    
Entity Registrant Name CRISPR THERAPEUTICS AG    
Entity Central Index Key 0001674416    
Entity Tax Identification Number 00-0000000    
Current Fiscal Year End Date --12-31    
Entity Well-known Seasoned Issuer Yes    
Entity Current Reporting Status Yes    
Entity Voluntary Filers No    
Entity Filer Category Large Accelerated Filer    
Entity Small Business false    
Entity Emerging Growth Company false    
Entity Shell Company false    
Entity File Number 001-37923    
Entity Address, Address Line One Baarerstrasse 14    
Entity Address, City or Town Zug    
Entity Address, Country CH    
Entity Address, Postal Zip Code 6300    
City Area Code 41 (0)41    
Local Phone Number 561 32 77    
Entity Interactive Data Current Yes    
Entity Incorporation, State or Country Code V8    
Document Annual Report true    
Document Transition Report false    
Entity Common Stock, Shares Outstanding   80,275,950  
Entity Public Float     $ 4.1
ICFR Auditor Attestation Flag true    
Document Financial Statement Error Correction Flag false    
Documents Incorporated by Reference

Portions of the Registrant’s Definitive Proxy Statement relating to the 2024 Annual General Meeting of Shareholders, which the Registrant intends to file with the Securities and Exchange Commission pursuant to Regulation 14A within 120 days after the end of the Registrant’s fiscal year ended December 31, 2023, are incorporated by reference into Part III of this Report.

    
Auditor Name Ernst & Young LLP    
Auditor Firm ID 42    
Auditor Location Boston, Massachusetts