Leases - Summary of Operating Lease Costs Included in Research and Development and General and Administrative Expense, as well as Sublease Income (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Leases [Abstract]
Operating lease costs	$ 34,896	$ 22,520	$ 14,342
Short-term lease costs	824	11,087	7,339
Variable lease costs	11,882	8,402	6,368
Sublease income		(5,253)	(587)
Net lease cost	$ 47,602	$ 36,756	$ 27,462