Condensed Consolidated Statements of Operations and Comprehensive (Loss) Income - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Revenue:
Total revenue	$ 94	$ 824	$ 1,192	$ 902,064
Operating expenses:
Research and development	116,622	83,500	358,090	237,472
General and administrative	27,001	23,709	81,295	76,012
Collaboration expense, net	38,859	22,464	103,427	69,354
Total operating expenses	182,482	129,673	542,812	382,838
(Loss) income from operations	(182,388)	(128,849)	(541,620)	519,226
Other income:
Other income, net	7,264	1,101	11,171	3,806
Total other income, net	7,264	1,101	11,171	3,806
Net (loss) income before income taxes	(175,124)	(127,748)	(530,449)	523,032
Benefit (provision) for income taxes	575	595	(9,151)	(4,123)
Net (loss) income	(174,549)	(127,153)	(539,600)	518,909
Foreign currency translation adjustment	(100)	(24)	(195)	(14)
Unrealized loss on marketable securities	(1,820)	(117)	(17,001)	(673)
Comprehensive (loss) income	$ (176,469)	$ (127,294)	$ (556,796)	$ 518,222
Net (loss) income per common share - basic	$ (2.24)	$ (1.67)	$ (6.96)	$ 6.85
Basic weighted-average common shares outstanding	78,021,520	76,288,534	77,547,771	75,712,437
Net (loss) income per common share - diluted	$ (2.24)	$ (1.67)	$ (6.96)	$ 6.44
Diluted weighted-average common shares outstanding	78,021,520	76,288,534	77,547,771	80,554,682
Collaboration Revenue [Member]
Revenue:
Total revenue	$ 94	$ 329	$ 430	$ 900,733
Grant Revenue [Member]
Revenue:
Total revenue	$ 0	$ 495	$ 762	$ 1,331