Condensed Consolidated Balance Sheets (Unaudited) - USD ($) $ in Thousands	Sep. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 494,151	$ 923,031
Marketable securities	1,401,824	1,456,098
Accounts receivable	49	305
Prepaid expenses and other current assets	36,679	38,079
Total current assets	1,932,703	2,417,513
Property and equipment, net	166,110	137,575
Marketable securities, non-current	77,147	0
Intangible assets, net	84	125
Restricted cash	12,123	16,913
Operating lease assets	161,507	174,460
Other non-current assets	3,682	5,291
Total assets	2,353,356	2,751,877
Current liabilities:
Accounts payable	32,114	14,816
Accrued expenses	102,954	91,003
Deferred revenue, current		1,011
Accrued tax liabilities	4,272	724
Operating lease liabilities	11,260	12,158
Other current liabilities	270	171
Total current liabilities	150,870	119,883
Deferred revenue, non-current	12,323	12,323
Operating lease liabilities, net of current portion	230,895	212,872
Other non-current liabilities	5,314	7,339
Total liabilities	399,402	352,417
Commitments and contingencies, see Note 6
Shareholders’ equity:
Common shares, CHF 0.03 par value, 150,347,467 and 145,364,335 shares authorized at September 30, 2022 and December 31, 2021, respectively, 78,428,146 and 77,170,382 shares issued at September 30, 2022 and December 31, 2021, respectively, 78,247,830 and 76,990,066 shares outstanding at September 30, 2022 and December 31, 2021, respectively	2,433	2,391
Treasury shares, at cost, 180,316 shares at September 30, 2022 and at December 31, 2021	(63)	(63)
Additional paid-in capital	2,709,361	2,598,114
Accumulated deficit	(735,515)	(195,915)
Accumulated other comprehensive loss	(22,262)	(5,067)
Total shareholders' equity	1,953,954	2,399,460
Total liabilities and shareholders’ equity	$ 2,353,356	$ 2,751,877