Condensed Consolidated Statements of Operations and Comprehensive (Loss) Income - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Revenue:
Total revenue	$ 158	$ 900,701	$ 1,098	$ 901,240
Operating expenses:
Research and development	123,223	82,332	241,468	153,971
General and administrative	26,273	28,806	54,294	52,303
Collaboration expense, net	33,922	26,945	64,568	46,891
Total operating expenses	183,418	138,083	360,330	253,165
(Loss) income from operations	(183,260)	762,618	(359,232)	648,075
Other income:
Other income, net	3,544	750	3,907	2,705
Total other income, net	3,544	750	3,907	2,705
Net (loss) income before income taxes	(179,716)	763,368	(355,325)	650,780
Provision for income taxes	(6,118)	(4,143)	(9,726)	(4,718)
Net (loss) income	(185,834)	759,225	(365,051)	646,062
Foreign currency translation adjustment	(69)	5	(95)	10
Unrealized loss on marketable securities	(3,380)	(173)	(15,180)	(556)
Comprehensive (loss) income	$ (189,283)	$ 759,057	$ (380,326)	$ 645,516
Net (loss) income per common share - basic	$ (2.40)	$ 10.01	$ (4.72)	$ 8.57
Basic weighted-average common shares outstanding	77,513,327	75,826,594	77,306,970	75,418,160
Net (loss) income per common share - diluted	$ (2.40)	$ 9.44	$ (4.72)	$ 8.03
Diluted weighted-average common shares outstanding	77,513,327	80,449,956	77,306,970	80,458,855
Collaboration Revenue [Member]
Revenue:
Total revenue	$ 158	$ 900,202	$ 336	$ 900,404
Grant Revenue [Member]
Revenue:
Total revenue	$ 0	$ 499	$ 762	$ 836