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Consolidated Statements of Operations and Comprehensive (Loss) Income - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Revenue:      
Total revenue $ 914,963 $ 719 $ 289,590
Operating expenses:      
Research and development [1] 438,633 266,946 179,362
General and administrative 102,802 88,208 63,488
Total operating expenses 541,435 355,154 242,850
Income (loss) from operations 373,528 (354,435) 46,740
Other income (expense):      
Loss from equity method investment     (5,467)
Other income, net 6,003 6,379 26,033
Total other income, net 6,003 6,379 20,566
Net income (loss) before income taxes 379,531 (348,056) 67,306
Provision for income taxes (1,870) (809) (448)
Net income (loss) 377,661 (348,865) 66,858
Foreign currency translation adjustment (11) 40 15
Unrealized loss on marketable securities (4,973) (130)  
Comprehensive income (loss) $ 372,677 $ (348,955) $ 66,873
Net income (loss) per common share - basic $ 4.97 $ (5.29) $ 1.23
Basic weighted-average common shares outstanding 75,948,686 65,949,672 54,392,304
Net income (loss) per common share - diluted $ 4.70 $ (5.29) $ 1.17
Diluted weighted-average common shares outstanding 80,393,496 65,949,672 56,932,798
Collaboration Revenue [Member]      
Revenue:      
Total revenue [2] $ 913,081 $ 543 $ 289,590
Grant Revenue [Member]      
Revenue:      
Total revenue $ 1,882 $ 176  
[1] Including the following amounts of research and development from a related party, see Note 9
[2] Including the following amounts of revenue from a related party, see Note 9