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Supplemental financial information - Prepaid expenses and other current assets (Details) - USD ($)
$ in Thousands
Jun. 30, 2022
Dec. 31, 2021
Supplemental financial information    
Prepaid clinical $ 3,515 $ 4,693
Prepaid insurance 50 1,122
Prepaid manufacturing costs 2,844 2,241
Other prepaid expenses and current assets 357 366
Total prepaid expenses and other current assets $ 6,766 $ 8,422