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Statements of Cash Flows - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2020
Jun. 30, 2019
Cash flows from operating activities:    
Net loss $ (27,227) $ (28,842)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization expense 211 233
Stock-based compensation expense 4,834 4,325
Changes in operating assets and liabilities:    
Prepaid expenses and other assets 1,889 (530)
Accounts receivable (46) 127
Accounts payable (60) (1,065)
Accrued expenses and other liabilities (946) (178)
Net cash used in operating activities (21,345) (25,930)
Cash flows from investing activities:    
Purchases of property and equipment (35) (43)
Net cash used in investing activities (35) (43)
Cash flows from financing activities:    
Proceeds from stock options exercised 473 251
Proceeds from public offering, net of underwriters' discounts 33,672  
Proceeds from at the market offering, net of sales commission 4,668  
Payment of offering costs (404) (24)
Net cash provided by financing activities 38,409 227
Net increase (decrease) in cash, cash equivalents and restricted cash 17,029 (25,746)
Cash, cash equivalents and restricted cash, at beginning of period 99,194 151,128
Cash, cash equivalents and restricted cash, at end of period 116,223 125,382
Supplemental disclosure of non-cash investing and financing activities:    
Offering costs not yet paid 12 $ 104
Property and equipment in accounts payable $ 38