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Supplemental financial information - Prepaid expenses and other current assets (Details) - USD ($)
$ in Thousands
Mar. 31, 2020
Dec. 31, 2019
Supplemental financial information    
Prepaid clinical $ 2,547 $ 3,719
Prepaid insurance 544 994
Prepaid Manufacturing Cost 717 558
Other prepaid expenses and current assets 306 366
Total prepaid expenses and other current assets $ 4,114 $ 5,637