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Organization (Details) - USD ($)
$ / shares in Units, $ in Thousands
12 Months Ended
Jun. 25, 2018
Jun. 07, 2018
Dec. 31, 2019
Dec. 31, 2018
Organization        
Accumulated deficit     $ (162,900)  
Cash and cash equivalents     $ 98,849 $ 150,637
Expected period of sufficient funds for planned operations     12 months  
Payment of offering costs     $ 182 $ 3,012
Reverse stock split ratio   0.03625    
Preferred stock, shares authorized     10,000,000 10,000,000
Preferred stock, par value (in dollars per share)     $ 0.01 $ 0.01
Preferred stock, shares issued     0 0
Preferred stock, shares outstanding     0 0
IPO        
Organization        
Common stock issued and sold in initial public offering (in shares) 7,359,998      
Public offering price of the shares sold $ 16.00      
Net proceeds from issuance of common stock $ 106,500      
Payment of offering costs $ 3,000      
Number of preferred stock converted into common stock 20,306,497      
Underwriters' option        
Organization        
Common stock issued and sold in initial public offering (in shares) 959,999