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Supplemental financial information - Prepaid expenses and other current assets (Details) - USD ($)
$ in Thousands
Sep. 30, 2019
Dec. 31, 2018
Supplemental financial information    
Prepaid clinical $ 1,970 $ 728
Prepaid insurance 1,220 673
Prepaid Manufacturing Cost 435  
Other prepaid expenses and current assets 355 383
Total prepaid expenses and other current assets $ 3,980 $ 1,784