X0306 4 2022-05-19 0001228627 Ocuphire Pharma, Inc. OCUP 0001674006 Sooch Mina C/O OCUPHIRE PHARMA, INC. 37000 GRAND RIVER AVE, SUITE 120 FARMINGTON HILLS MI 48335 true true President and CEO Common Stock 2022-05-19 4 P 0 12500 2.0703 A 412522 D Common Stock 2022-05-20 4 P 0 12500 2.024 A 425022 D The price represents the weighted average price of the multiple transactions reported on this line. The shares were purchased at prices ranging from $2.045 to $2.10. Upon request by the SEC staff, the issuer or any securityholder of the issuer, the reporting person will provide full information regarding the number of shares purchased at each separate price. The price represents the weighted average price of the multiple transactions reported on this line. The shares were purchased at prices ranging from $2.015 to $2.025. Upon request by the SEC staff, the issuer or any securityholder of the issuer, the reporting person will provide full information regarding the number of shares purchased at each separate price. /s/ Emily J. Johns, by Power of Attorney 2022-05-23