Commitments - Additional Information (Details)	1 Months Ended			12 Months Ended
	Feb. 28, 2019 ft²	Apr. 30, 2018 ft²	May 31, 2015 ft²	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)
Lessee Lease Description [Line Items]
Lease expiration period			2022-05
Additional laboratory and office facilities under lease	6,378	6,378
Increased of leased premises		36,754
Lessee operating lease extended lease term		2026-11
Lease existence of option to extend			true
Lessee operating lease option to extend			5 years
Lease termination term	2020-07
Operating lease rent expense | $				$ 2,300,000	$ 2,100,000
Contingency losses, accrued | $				$ 0	$ 0
South San Francisco and California
Lessee Lease Description [Line Items]
Laboratory and office facilities under lease			30,376