CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($) $ in Thousands	Total	At The Market	Public Offering	Common Stock	Common Stock At The Market	Common Stock Public Offering	Additional Paid-In Capital	Additional Paid-In Capital At The Market	Additional Paid-In Capital Public Offering	Accumulated Deficit	Accumulated Other Comprehensive Income (Loss)
Beginning balance at Dec. 31, 2020	$ 104,179			$ 2			$ 319,196			$ (214,842)	$ (177)
Beginning balance, shares at Dec. 31, 2020				24,773,361
Issuance of common stock from of net issuance costs		$ 4,690	$ 134,770			$ 1		$ 4,690	$ 134,769
Issuance of common stock from net of issuance costs, shares					214,971	4,356,060
Issuances of common stock from employee stock plans	2,022						2,022
Issuances of common stock from employee stock plans, shares				210,727
Stock-based compensation	9,952						9,952
Foreign currency translation gain	258										258
Unrealized loss on marketable securities	(287)										(287)
Net loss	(69,204)									(69,204)
Ending balance at Dec. 31, 2021	$ 186,380			$ 3			470,629			(284,046)	(206)
Ending balance, shares at Dec. 31, 2021	29,555,119			29,555,119
Proceeds from sale of pre-funded warrants in private placement, net of issuance costs	$ 49,785						49,785
Issuance of common stock from of net issuance costs		$ 4,978	$ 75,025					$ 4,978	$ 75,025
Issuance of common stock from net of issuance costs, shares					209,349	4,338,104
Issuances of common stock from employee stock plans	1,392						1,392
Issuances of common stock from employee stock plans, shares				151,742
Stock-based compensation	11,264						11,264
Foreign currency translation gain	627										627
Unrealized loss on marketable securities	(447)										(447)
Net loss	(83,838)									(83,838)
Ending balance at Dec. 31, 2022	$ 245,166			$ 3			$ 613,073			$ (367,884)	$ (26)
Ending balance, shares at Dec. 31, 2022	34,254,314			34,254,314