Collaboration Agreements - Additional Information (Details) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021	Apr. 30, 2020	Dec. 31, 2019
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue recognized	$ 886,000	$ 869,000	$ 1,527,000	$ 2,091,000
Collaboration and License Agreement | Hanmi Pharmaceutical Co., LTD
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Upfront and near-term milestone payment	10,400,000		10,400,000				$ 10,000,000.0
Upfront fee	4,000,000.0		4,000,000.0				4,000,000.0
Milestone payment	6,000,000.0		6,000,000.0			$ 6,000,000.0
Milestone payment related to supply	400,000		400,000
Revenue recognized	900,000	$ 900,000	1,500,000	$ 2,100,000
Deferred revenue	$ 0		$ 0		$ 1,500,000
Collaboration and License Agreement | Hanmi Pharmaceutical Co., LTD | Maximum
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Contingent payments upon achievement of specified milestones							$ 108,000,000.0