J.P. Morgan Securities LLC

383 Madison Avenue

New York, NY 10179

Credit Suisse Securities (USA) LLC

Eleven Madison Avenue

New York, NY 10010

BofA Securities, Inc.

One Bryant Park

New York, NY 10036

Cowen and Company, LLC

599 Lexington Avenue, 20th Floor

New York, NY 10022

Stifel, Nicolaus & Company, Incorporated

One Montgomery Street, Suite 3700

San Francisco, CA 94104

July 19, 2021

VIA EDGAR

Office of Life Sciences

Division of Corporation Finance

Securities and Exchange Commission

100 F Street, N.E.

Washington, D.C. 20549

Attention:     Cara Wirth

    Mark Ransom

Re:    Absci Corporation

Request for Acceleration of Effective Date

    File No. 333-257553

Ladies and Gentlemen:

In accordance with Rule 461 under the Securities Act of 1933, as amended (the “Act”), we, as representatives of the several underwriters of Absci Corporation’s (the “Company”) proposed public offering of its common stock, par value $0.0001 per share, hereby join the Company’s request for acceleration of the above-referenced Registration Statement, as amended, requesting effectiveness as of 5:30 p.m. Eastern Time on July 21, 2021, or as soon thereafter as is practicable, or at such later time as the Company or its outside counsel, Goodwin Procter LLP, may request via telephone call to the staff of the Division of Corporation Finance of the Securities and Exchange Commission.

Pursuant to Rule 460 of the Act, we, as representatives of the several underwriters, wish to advise you that we have distributed approximately 2,033 copies of the Company’s Preliminary Prospectus dated July 15, 2021 through the date hereof to underwriters, dealers, institutions and others.

We, the undersigned, as representatives of the several underwriters, have complied and will continue to comply, and we have been informed by the participating underwriters that they have complied and will continue to comply, with the provisions of Rule 15c2-8 of the Securities Exchange Act of 1934, as amended.

[Signature page follows]

Very truly yours,
J.P. Morgan Securities LLC
Credit Suisse Securities (USA) LLC
BofA Securities, Inc.
Cowen and Company, LLC
Stifel, Nicolaus & Company, Incorporated
As representatives of the several Underwriters
By: J.P. Morgan Securities LLC
	By:	/s/ Benjamin Burdett
	Name:	Benjamin Burdett
	Title:	Managing Director
By: Credit Suisse Securities (USA) LLC
	By:	/s/ Sumit Khedekar
	Name:	Sumit Khedekar
	Title:	Americas Head of Healthcare
By: BofA Securities, Inc.
	By:	/s/ Greg Butz
	Name:	Greg Butz
	Title:	Managing Director
By: Cowen and Company, LLC
	By:	/s/ Jamie Streator
	Name:	Jamie Streator
	Title:	Managing Director
By: Stifel, Nicolaus & Company, Incorporated
	By:	/s/ Nathan Thompson
	Name:	Nathan Thompson
	Title:	Director

[Signature Page to Acceleration Request Letter]