Stock-Based Compensation - Summary of Stock Option Activity (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended	12 Months Ended
Mar. 31, 2022	Dec. 31, 2021
Compensation Related Costs [Abstract]
Number of Shares, Beginning Balance	2,373,024
Number of Shares, Granted	442,339
Number of Shares, Forfeited	(30,651)
Number of Shares, Ending Balance	2,784,712	2,373,024
Number of Shares, Options vested and exercisable	1,106,407
Weighted-Average Exercise Price, Beginning Balance	$ 9.63
Weighted-Average Exercise Price, Granted	1.38
Weighted-Average Exercise Price, Forfeited	8.12
Weighted-Average Exercise Price, Ending Balance	8.34	$ 9.63
Weighted-Average Exercise Price, Options vested and exercisable	$ 8.04
Weighted-Average Remaining Contractual Term, Outstanding	8 years 3 months 7 days	8 years 2 months 8 days
Weighted-Average Remaining Contractual Term, Options vested and exercisable	7 years 4 months 6 days
Aggregate Intrinsic Value, Balance	$ 219

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The number of shares under options that were cancelled during the reporting period as a result of occurrence of a terminating event specified in contractual agreements pertaining to the stock option plan.

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Gross number of share options (or share units) granted during the period.

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Amount by which the current fair value of the underlying stock exceeds the exercise price of options outstanding.

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Number of options outstanding, including both vested and non-vested options.

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Weighted average price at which grantees can acquire the shares reserved for issuance under the stock option plan.

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- Definition

Number of fully vested and expected to vest exercisable options that may be converted into shares under option plan. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur.

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Weighted-average exercise price, at which grantee can acquire shares reserved for issuance, for fully vested and expected to vest exercisable or convertible options. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur.

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Weighted average price at which grantees could have acquired the underlying shares with respect to stock options that were terminated.

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Weighted average per share amount at which grantees can acquire shares of common stock by exercise of options.

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Weighted average remaining contractual term for option awards outstanding, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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Weighted average remaining contractual term for fully vested and expected to vest exercisable or convertible options, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur.

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