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License and Purchase Agreements - Additional Information (Details) - USD ($)
1 Months Ended 12 Months Ended 69 Months Ended
Oct. 31, 2020
Apr. 30, 2016
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2021
Dec. 31, 2019
License And Purchase Agreements [Line Items]            
Common stock, shares issued     26,287,264 17,548,263 26,287,264  
Lundbeck | Lundbeck Agreement            
License And Purchase Agreements [Line Items]            
Maximum development milestones payments due   $ 23,500,000        
Maximum development milestones payments due for other than licensed product   $ 11,800,000        
Upfront and ongoing milestone payments     $ 0 $ 0    
Common stock, shares issued   167,523       443,271
Outstanding equity percentage pursuant to restricted stock agreement   8.00%        
Notice period for agreement termination     180 days      
Lundbeck | Lundbeck Agreement | Research and Development Expense            
License And Purchase Agreements [Line Items]            
Upfront and ongoing milestone payments         $ 1,800,000  
Complexa ABC | Complexa APA            
License And Purchase Agreements [Line Items]            
Milestone payment triggered under agreement.     $ 0   $ 0  
Complexa ABC | Complexa APA | Maximum            
License And Purchase Agreements [Line Items]            
Milestones payments payable based on achievement of specified clinical and commercial sale milestones $ 3,800,000          
Complexa ABC | Complexa APA | Research and Development Expense            
License And Purchase Agreements [Line Items]            
One-time payment to acquire right, title and interest in and to certain assets $ 100,000