Stock-Based Compensation (Tables)

12 Months Ended

Dec. 31, 2021

Compensation Related Costs [Abstract]

Summary of Stock Option Activity

The following table summarizes the Company’s stock option activity:

	Number of Shares			Weighted- Average Exercise Price		Weighted- Average Remaining Contractual Term (in years)		Aggregate Intrinsic Value (in thousands)
Outstanding as of December 31, 2020		1,935,632		$	9.85		8.14
Granted		952,953			10.19
Exercised		(158,681	)		4.34
Forfeited		(356,880	)		14.69
Outstanding as of December 31, 2021		2,373,024		$	9.63	8.19		$	—
Options vested and exercisable as of December 31, 2021		880,958		$	7.07	7.33		$	—

Summary of Stock-Based Compensation Fair Value Assumptions

The assumptions that the Company used to determine the grant date fair value of stock options granted to employees, non-employees and members of the Board during the years ended December 31, 2021 and 2020 were as follows, presented on a weighted-average basis:

	Year Ended December 31,
	2021			2020
Expected term (in years)		6.20			6.17
Expected volatility		81.0	%		74.7	%
Expected dividend yield		0.00	%		0.00	%
Risk-free interest rate		0.81	%		0.52	%

Summary of Stock-Based Compensation Expense

Stock-based compensation expense included in the Company’s consolidated statements of operations and comprehensive loss is as follows (in thousands):

	Year Ended December 31,
	2021		2020
General and administrative	$	2,441	$	1,490
Research and development		1,404		741
Total stock-based compensation expense	$	3,845	$	2,231