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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Cash flows from operating activities      
Net loss $ (55,287) $ (52,543) $ (180,029)
Adjustments for:      
Share-based compensation expense 32,469 32,888 48,894
Depreciation 4,090 5,335 7,591
Unrealized foreign exchange losses (gains) 13,827 (14,482) 99
Loss on loan extinguishment 0 1,686 0
Non-cash lease expense 1,647 2,076 2,076
Other 412 (4) 222
Changes in assets and liabilities:      
Increase in accounts receivable (17,871) (26,264) (4,863)
Decrease (increase) in prepayments and other current assets 8,544 (14,694) 1,350
Increase in accounts payable 2,625 4,913 1,474
Increase in accrued expenses 39,088 41,757 10,681
Decrease in deferred revenue (8,013) (25,504) (29,072)
Decrease in operating lease liabilities (2,226) (1,782) (2,013)
(Increase) decrease in other operating assets (15,012) (4,729) 361
(Decrease) increase in other operating liabilities (1,353) 2,138 123
Net cash provided by (used in) operating activities 2,940 (49,209) (143,106)
Cash flows from investing activities      
Proceeds from sale of property, plant and equipment 0 6 106
Purchase of property, plant and equipment (5,425) (2,203) (1,386)
Net cash used in investing activities (5,425) (2,197) (1,280)
Cash flows from financing activities      
Proceeds from issue of ordinary shares, net 0 139,515 286,887
Exercise of share options 34,346 9,696 1,298
Loan repayments 0 (50,000) 0
Debt prepayments and extinguishments 0 (2,000) 0
Non-current interest-bearing loan received 0 50,000 0
Debt issuance payments 0 (1,769) 0
Net cash provided by financing activities 34,346 145,442 288,185
Increase in net cash and cash equivalents 31,861 94,036 143,799
Net foreign exchange difference on cash held 8,293 (12,646) 625
Cash and cash equivalents at beginning of year 402,472 321,082 176,658
Cash and cash equivalents at end of year 442,626 402,472 321,082
Supplemental cash flow information      
Cash received (paid) for interest, net 5,674 (4,482) (5,708)
Cash received (paid) for income taxes, net $ (977) $ (765) $ 17,044