Consolidated Statements of Shareholders' Equity - USD ($) $ in Thousands	Ordinary Shares [Member]	Deferred Shares [Member]	Additional Paid-in Capital [Member]	Accumulated Deficit [Member]	Accumulated Other Comprehensive (Loss) Income [Member]	Total
Balance at Dec. 31, 2020	$ 86	$ 1	$ 563,698	$ (456,815)	$ (30,061)	$ 76,909
Balance (in shares) at Dec. 31, 2020	31,782,885	5,793,501
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	$ 0	$ 0	0	(180,029)	0	(180,029)
Other comprehensive income (loss)	0	0	0	0	(254)	(254)
Issuance of ordinary share, net	$ 32		286,855	0	0	286,887
Issuance of ordinary share, net (in shares)	12,003,203
Exercise of share options	$ 0	$ 0	1,298	0	0	$ 1,298
Exercise of share options (in shares)	76,762	0				76,762
Share-based compensation expense	$ 0	$ 0	48,894	0	0	$ 48,894
Balance at Dec. 31, 2021	$ 118	$ 1	900,745	(636,844)	(30,315)	233,705
Balance (in shares) at Dec. 31, 2021	43,862,850	5,793,501
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	$ 0	$ 0	0	(52,543)	0	(52,543)
Other comprehensive income (loss)	0	0	0	0	(24,358)	(24,358)
Issuance of ordinary share, net	$ 10		139,505	0	0	139,515
Issuance of ordinary share, net (in shares)	3,733,333
Exercise of share options	$ 1	$ 0	9,695	0	0	$ 9,696
Exercise of share options (in shares)	492,163	0				492,163
Share-based compensation expense	$ 0	$ 0	32,888	0	0	$ 32,888
Balance at Dec. 31, 2022	$ 129	$ 1	1,082,833	(689,387)	(54,673)	$ 338,903
Balance (in shares) at Dec. 31, 2022	48,088,346	5,793,501				48,088,346
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	$ 0	$ 0	0	(55,287)	0	$ (55,287)
Other comprehensive income (loss)	0	0	0	0	18,412	18,412
Exercise of share options	$ 5	$ 0	34,341	0	0	$ 34,346
Exercise of share options (in shares)	1,637,303	0				1,637,303
Share-based compensation expense	$ 0	$ 0	32,469	0	0	$ 32,469
Balance at Dec. 31, 2023	$ 134	$ 1	$ 1,149,643	$ (744,674)	$ (36,261)	$ 368,843
Balance (in shares) at Dec. 31, 2023	49,725,649	5,793,501				49,725,649