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  <headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
    <previousAccessionNumber>0001085146-25-001358</previousAccessionNumber>
    <filerInfo>
      <filer>
        <filerCredentials>
          <!-- Field: Pseudo-Tag; ID: Name; Data: PRIMECAP MANAGEMENT CO/CA/ -->
          <cik>0000763212</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>1</amendmentNo>
      <securitiesClassTitle>ADR</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>06/30/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001671927</issuerCik>
        <issuerName>Immunocore Holdings plc - ADR</issuerName>
        <issuerCusip>45258D105</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>92 Park Drive Milton Park</com:street1>
          <com:city>Abingdon, Oxfordshire</com:city>
          <com:stateOrCountry>X0</com:stateOrCountry>
          <com:zipCode>OX14 4RY</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(b)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>PRIMECAP MANAGEMENT CO/CA/</reportingPersonName>
      <citizenshipOrOrganization>X1</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>3746574.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>3772234.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>3772234.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>7.51</classPercent>
      <typeOfReportingPerson>IA</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>Immunocore Holdings plc - ADR</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>92 Park Drive Milton Park, Abingdon, Oxfordshire, UNITED KINGDOM OX14 4RY</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>PRIMECAP MANAGEMENT CO/CA/</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>177 EAST COLORADO BLVD.
11TH FLOOR
PASADENA, California
91105</principalBusinessOfficeOrResidenceAddress>
        <citizenship>PRIMECAP MANAGEMENT CO/CA/ - UNITED STATES</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>N</notApplicableFlag>
        <typeOfPersonFiling>IA</typeOfPersonFiling>
      </item3>
      <item4>
        <amountBeneficiallyOwned>3,772,234</amountBeneficiallyOwned>
        <classPercent>7.51</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>PRIMECAP MANAGEMENT CO/CA/ - 3,746,574</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>PRIMECAP MANAGEMENT CO/CA/ - 0</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>PRIMECAP MANAGEMENT CO/CA/ - 3,772,234</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>PRIMECAP MANAGEMENT CO/CA/ - 0</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
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      <item5>
        <notApplicableFlag>Y</notApplicableFlag>
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      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
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      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
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      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
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      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
      </item10>
    </items>
    <signatureInformation>
      <reportingPersonName>PRIMECAP MANAGEMENT CO/CA/</reportingPersonName>
      <signatureDetails>
        <signature>Jorge A. Rodriguez</signature>
        <title>Deputy Chief Compliance Officer</title>
        <date>08/14/2025</date>
      </signatureDetails>
    </signatureInformation>
  </formData>
</edgarSubmission>
