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Condensed Statements of Cash Flows - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Cash flows from operating activities:    
Net loss $ (44,060) $ (43,363)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization expense 431 395
Stock-based compensation 10,089 9,015
Non-cash lease expense 513 565
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets 2,293 749
Accounts payable and accrued expenses (3,563) 6,789
Lease liability (598) (486)
Net cash used in operating activities (34,895) (26,336)
Cash flows from investing activities:    
Purchase of property and equipment (618) (735)
Net cash used in investing activities (618) (735)
Cash flows from financing activities:    
Principal payments on term loan payable 0 (846)
Proceeds from exercise of common stock options and employee stock purchase plan 158 1,037
Net cash provided by financing activities 158 191
Change in cash, cash equivalents, and restricted cash (35,355) (26,880)
Cash, cash equivalents, and restricted cash at beginning of period 254,295 386,919
Cash, cash equivalents, and restricted cash at end of period 218,940 360,039
Supplemental disclosure of cash flow information:    
Right-of-use assets and lease liabilities derecognized $ (303) $ 0