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Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Cash flows from operating activities:    
Net loss $ (89,478) $ (32,947)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation expense 783 637
Stock-based compensation 19,187 2,640
Non-cash lease expense 1,146 1,073
Amortization of debt issuance costs 2 31
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets (3,360) (3,535)
Accounts payable and accrued expenses 6,034 1,790
Lease liability (1,074) (885)
Net cash used in operating activities (66,760) (31,196)
Cash flows from investing activities:    
Purchases of available-for-sale securities (65,106) 0
Purchase of property and equipment (1,372) (917)
Net cash used in investing activities (66,478) (917)
Cash flows from financing activities:    
Proceeds from issuance of redeemable convertible preferred stock, net of issuance costs 0 153,351
Proceeds from issuance of common stock upon initial public offering, net of underwriting discounts and commissions 0 258,284
Payment of deferred offering costs 0 (2,606)
Principal payments on term loan payable (846) (700)
Proceeds from exercise of common stock options and employee stock purchase plan 1,460 177
Net cash provided by financing activities 614 408,506
Change in cash, cash equivalents, and restricted cash (132,624) 376,393
Cash, cash equivalents, and restricted cash at beginning of period 386,919 10,526
Cash, cash equivalents, and restricted cash at end of period 254,295 386,919
Supplemental disclosure of cash flow information:    
Unpaid initial public offering costs included in accounts payable and accrued expenses 0 339
Right-of-use assets and lease liabilities recognized 3,699 0
Issuance of Series B redeemable convertible preferred stock upon conversion of convertible notes 0 10,095
Conversion of redeemable convertible preferred stock upon closing of initial public offering $ 0 $ 216,567