CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Income Statement [Abstract]
Royalty revenue	$ 3,114	$ 12,292
Revenue from Contract with Customer, Product and Service [Extensible List]	us-gaap:RoyaltyMember	us-gaap:RoyaltyMember
Operating expenses:
Research and development	$ (17,882)	$ (18,994)
General and administrative	(13,873)	(14,698)
Loss from operations	(28,641)	(21,400)
Other income (expense):
Other expense from continuing operations, net	(4,027)	(8,008)
Gain on extinguishment of liability related to sale of royalties	37,182
Milestone income related to sale of royalties	2,500
Net income (loss) from continuing operations	7,014	(29,408)
Discontinued operations:
Income from discontinued operations	1,013	951
Net income (loss)	$ 8,027	$ (28,457)
Net income (loss) per share:
Basic	$ 1.57	$ (6.07)
Diluted	$ 1.57	$ (6.07)
Shares used in calculation:
Basic	5,100,310	4,687,952
Diluted	5,102,914	4,687,952