3.23.1 html 140 362 1 false 49 0 false 7 false false R1.htm 100000 - Document - Document and Entity Information Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DocumentDocumentAndEntityInformation Document and Entity Information Cover 1 false false R2.htm 100010 - Statement - CONSOLIDATED BALANCE SHEETS Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_StatementCONSOLIDATEDBALANCESHEETS CONSOLIDATED BALANCE SHEETS Statements 2 false false R3.htm 100020 - Statement - CONSOLIDATED BALANCE SHEETS (Parenthetical) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_StatementCONSOLIDATEDBALANCESHEETSParenthetical CONSOLIDATED BALANCE SHEETS (Parenthetical) Statements 3 false false R4.htm 100030 - Statement - CONSOLIDATED STATEMENTS OF OPERATIONS Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_StatementCONSOLIDATEDSTATEMENTSOFOPERATIONS CONSOLIDATED STATEMENTS OF OPERATIONS Statements 4 false false R5.htm 100040 - Statement - CONSOLIDATED STATEMENTS OF CASH FLOWS Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_StatementCONSOLIDATEDSTATEMENTSOFCASHFLOWS CONSOLIDATED STATEMENTS OF CASH FLOWS Statements 5 false false R6.htm 100050 - Statement - CONSOLIDATED STATEMENT OF CHANGES IN STOCKHOLDERS' EQUITY Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_StatementCONSOLIDATEDSTATEMENTOFCHANGESINSTOCKHOLDERSEQUITY CONSOLIDATED STATEMENT OF CHANGES IN STOCKHOLDERS' EQUITY Statements 6 false false R7.htm 100060 - Disclosure - Nature of Business and Significant Accounting Policies Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureNatureOfBusinessAndSignificantAccountingPolicies Nature of Business and Significant Accounting Policies Notes 7 false false R8.htm 100070 - Disclosure - Discontinued Operations Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureDiscontinuedOperations Discontinued Operations Notes 8 false false R9.htm 100080 - Disclosure - Collaboration Agreements Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureCollaborationAgreements Collaboration Agreements Notes 9 false false R10.htm 100090 - Disclosure - Fair Value Measurements Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureFairValueMeasurements Fair Value Measurements Notes 10 false false R11.htm 100100 - Disclosure - Cash, Cash Equivalents, and Restricted Cash Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureCashCashEquivalentsAndRestrictedCash Cash, Cash Equivalents, and Restricted Cash Notes 11 false false R12.htm 100110 - Disclosure - Property and Equipment, Net Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosurePropertyAndEquipmentNet Property and Equipment, Net Notes 12 false false R13.htm 100120 - Disclosure - Debt Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureDebt Debt Notes 13 false false R14.htm 100130 - Disclosure - Liability Related to Sale of Future Royalties Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureLiabilityRelatedToSaleOfFutureRoyalties Liability Related to Sale of Future Royalties Notes 14 false false R15.htm 100140 - Disclosure - Leases and Contingencies Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureLeasesAndContingencies Leases and Contingencies Notes 15 false false R16.htm 100150 - Disclosure - Net Income (Loss) per Share Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureNetIncomeLossPerShare Net Income (Loss) per Share Notes 16 false false R17.htm 100160 - Disclosure - Equity Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureEquity Equity Notes 17 false false R18.htm 100170 - Disclosure - 401(K) Savings Plan Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_Disclosure401KSavingsPlan 401(K) Savings Plan Notes 18 false false R19.htm 100180 - Disclosure - Income Taxes Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureIncomeTaxes Income Taxes Notes 19 false false R20.htm 100190 - Disclosure - Subsequent Events Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureSubsequentEvents Subsequent Events Notes 20 false false R21.htm 100200 - Disclosure - Nature of Business and Significant Accounting Policies (Policies) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureNatureOfBusinessAndSignificantAccountingPoliciesPolicies Nature of Business and Significant Accounting Policies (Policies) Policies http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureNatureOfBusinessAndSignificantAccountingPolicies 21 false false R22.htm 100210 - Disclosure - Nature of Business and Significant Accounting Policies (Tables) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureNatureOfBusinessAndSignificantAccountingPoliciesTables Nature of Business and Significant Accounting Policies (Tables) Tables http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureNatureOfBusinessAndSignificantAccountingPolicies 22 false false R23.htm 100220 - Disclosure - Discontinued Operations (Tables) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureDiscontinuedOperationsTables Discontinued Operations (Tables) Tables http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureDiscontinuedOperations 23 false false R24.htm 100230 - Disclosure - Cash, Cash Equivalents, and Restricted Cash (Tables) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureCashCashEquivalentsAndRestrictedCashTables Cash, Cash Equivalents, and Restricted Cash (Tables) Tables http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureCashCashEquivalentsAndRestrictedCash 24 false false R25.htm 100240 - Disclosure - Property and Equipment, Net (Tables) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosurePropertyAndEquipmentNetTables Property and Equipment, Net (Tables) Tables http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosurePropertyAndEquipmentNet 25 false false R26.htm 100250 - Disclosure - Debt (Tables) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureDebtTables Debt (Tables) Tables http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureDebt 26 false false R27.htm 100260 - Disclosure - Liability Related to Sale of Future Royalties (Tables) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureLiabilityRelatedToSaleOfFutureRoyaltiesTables Liability Related to Sale of Future Royalties (Tables) Tables http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureLiabilityRelatedToSaleOfFutureRoyalties 27 false false R28.htm 100270 - Disclosure - Leases and Contingencies (Tables) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureLeasesAndContingenciesTables Leases and Contingencies (Tables) Tables http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureLeasesAndContingencies 28 false false R29.htm 100280 - Disclosure - Net Income (Loss) per Share (Tables) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureNetIncomeLossPerShareTables Net Income (Loss) per Share (Tables) Tables http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureNetIncomeLossPerShare 29 false false R30.htm 100290 - Disclosure - Equity (Tables) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureEquityTables Equity (Tables) Tables http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureEquity 30 false false R31.htm 100300 - Disclosure - Income Taxes (Tables) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureIncomeTaxesTables Income Taxes (Tables) Tables http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureIncomeTaxes 31 false false R32.htm 100310 - Disclosure - Nature of Business and Significant Accounting Policies - Additional Information (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureNatureOfBusinessAndSignificantAccountingPoliciesAdditionalInformationDetails Nature of Business and Significant Accounting Policies - Additional Information (Details) Details 32 false false R33.htm 100320 - Disclosure - Nature of Business and Significant Accounting Policies - Schedule of Estimated Useful Lives of Property and Equipment (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureNatureOfBusinessAndSignificantAccountingPoliciesScheduleOfEstimatedUsefulLivesOfPropertyAndEquipmentDetails Nature of Business and Significant Accounting Policies - Schedule of Estimated Useful Lives of Property and Equipment (Details) Details 33 false false R34.htm 100330 - Disclosure - Discontinued Operations - Additional Information (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureDiscontinuedOperationsAdditionalInformationDetails Discontinued Operations - Additional Information (Details) Details 34 false false R35.htm 100340 - Disclosure - Discontinued Operations - Summary of Reconciliation of Carrying Amounts of Assets and Liabilities and Income (Loss) from Discontinued Operation (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/DisclosureDiscontinuedOperationsSummaryOfReconciliationOfCarryingAmountsOfAssetsAndLiabilitiesAndIncomeLossFromDiscontinuedOperationDetails Discontinued Operations - Summary of Reconciliation of Carrying Amounts of Assets and Liabilities and Income (Loss) from Discontinued Operation (Details) Details 35 false false R36.htm 100350 - Disclosure - Collaboration Agreements - Additional Information (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureCollaborationAgreementsAdditionalInformationDetails Collaboration Agreements - Additional Information (Details) Details 36 false false R37.htm 100360 - Disclosure - Fair Value Measurements - Additional Information (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureFairValueMeasurementsAdditionalInformationDetails Fair Value Measurements - Additional Information (Details) Details 37 false false R38.htm 100370 - Disclosure - Cash, Cash Equivalents, and Restricted Cash - Additional Information (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureCashCashEquivalentsAndRestrictedCashAdditionalInformationDetails Cash, Cash Equivalents, and Restricted Cash - Additional Information (Details) Details 38 false false R39.htm 100380 - Disclosure - Cash, Cash Equivalents, and Restricted Cash - Schedule of Cash, Cash Equivalents and Restricted Cash, Both Current and Long-term Portion (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureCashCashEquivalentsAndRestrictedCashScheduleOfCashCashEquivalentsAndRestrictedCashBothCurrentAndLongTermPortionDetails Cash, Cash Equivalents, and Restricted Cash - Schedule of Cash, Cash Equivalents and Restricted Cash, Both Current and Long-term Portion (Details) Details 39 false false R40.htm 100390 - Disclosure - Property and Equipment, Net - Summary of Property and Equipment (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosurePropertyAndEquipmentNetSummaryOfPropertyAndEquipmentDetails Property and Equipment, Net - Summary of Property and Equipment (Details) Details 40 false false R41.htm 100400 - Disclosure - Property and Equipment, Net - Additional Information (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosurePropertyAndEquipmentNetAdditionalInformationDetails Property and Equipment, Net - Additional Information (Details) Details 41 false false R42.htm 100410 - Disclosure - Debt - Additional Information (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureDebtAdditionalInformationDetails Debt - Additional Information (Details) Details 42 false false R43.htm 100420 - Disclosure - Debt - Schedule of Future Principal, Interest, and Other Related Fee Payments in Connection with the Credit Agreement (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/DisclosureDebtScheduleOfFuturePrincipalInterestAndOtherRelatedFeePaymentsInConnectionWithTheCreditAgreementDetails Debt - Schedule of Future Principal, Interest, and Other Related Fee Payments in Connection with the Credit Agreement (Details) Details 43 false false R44.htm 100430 - Disclosure - Liability Related to Sale of Future Royalties - Additional Information (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureLiabilityRelatedToSaleOfFutureRoyaltiesAdditionalInformationDetails Liability Related to Sale of Future Royalties - Additional Information (Details) Details 44 false false R45.htm 100440 - Disclosure - Schedule of Changes in the Liability Related to the Sale of Future Royalties (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureScheduleOfChangesInLiabilityRelatedToSaleOfFutureRoyaltiesDetails Schedule of Changes in the Liability Related to the Sale of Future Royalties (Details) Details 45 false false R46.htm 100450 - Disclosure - Leases and Contingencies - Additional Information (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureLeasesAndContingenciesAdditionalInformationDetails Leases and Contingencies - Additional Information (Details) Details 46 false false R47.htm 100460 - Disclosure - Leases and Contingencies - Components of Lease Expense (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureLeasesAndContingenciesComponentsOfLeaseExpenseDetails Leases and Contingencies - Components of Lease Expense (Details) Details 47 false false R48.htm 100470 - Disclosure - Leases and Contingencies - Summary of Right of Use Assets Acquired Under Operating Leases (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureLeasesAndContingenciesSummaryOfRightOfUseAssetsAcquiredUnderOperatingLeasesDetails Leases and Contingencies - Summary of Right of Use Assets Acquired Under Operating Leases (Details) Details 48 false false R49.htm 100480 - Disclosure - Leases and Contingencies - Summary of Future Minimum Lease Payments (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureLeasesAndContingenciesSummaryOfFutureMinimumLeasePaymentsDetails Leases and Contingencies - Summary of Future Minimum Lease Payments (Details) Details 49 false false R50.htm 100490 - Disclosure - Net Income (Loss) Per Share - Computation of Basic and Diluted Net Income (Loss) per Share (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/DisclosureNetIncomeLossPerShareComputationOfBasicAndDilutedNetIncomeLossPerShareDetails Net Income (Loss) Per Share - Computation of Basic and Diluted Net Income (Loss) per Share (Details) Details http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureNetIncomeLossPerShareTables 50 false false R51.htm 100500 - Disclosure - Net Income (Loss) Per Share - Summary of Potentially Dilutive Shares Excluded from Calculation of Net Loss Per Share (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/DisclosureNetIncomeLossPerShareSummaryOfPotentiallyDilutiveSharesExcludedFromCalculationOfNetLossPerShareDetails Net Income (Loss) Per Share - Summary of Potentially Dilutive Shares Excluded from Calculation of Net Loss Per Share (Details) Details http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureNetIncomeLossPerShareTables 51 false false R52.htm 100510 - Disclosure - Equity - Additional Information (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureEquityAdditionalInformationDetails Equity - Additional Information (Details) Details 52 false false R53.htm 100530 - Disclosure - Equity - Summary of Stock-based Compensation Expense Includes Amortization of Stock Options and Restricted Stock Units Granted (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureEquitySummaryOfStockBasedCompensationExpenseIncludesAmortizationOfStockOptionsAndRestrictedStockUnitsGrantedDetails Equity - Summary of Stock-based Compensation Expense Includes Amortization of Stock Options and Restricted Stock Units Granted (Details) Details 53 false false R54.htm 100540 - Disclosure - Equity - Assumptions used in Valuing the Stock Options Granted under Black-Scholes Valuation Model (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureEquityAssumptionsUsedInValuingStockOptionsGrantedUnderBlackScholesValuationModelDetails Equity - Assumptions used in Valuing the Stock Options Granted under Black-Scholes Valuation Model (Details) Details 54 false false R55.htm 100550 - Disclosure - Equity - Summary of Stock Option Activity (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureEquitySummaryOfStockOptionActivityDetails Equity - Summary of Stock Option Activity (Details) Details 55 false false R56.htm 100560 - Disclosure - Equity - Summary of Restricted Stock Activity (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureEquitySummaryOfRestrictedStockActivityDetails Equity - Summary of Restricted Stock Activity (Details) Details 56 false false R57.htm 100570 - Disclosure - 401(K) Savings Plan - Additional Information (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_Disclosure401KSavingsPlanAdditionalInformationDetails 401(K) Savings Plan - Additional Information (Details) Details 57 false false R58.htm 100580 - Disclosure - Income Taxes - Additional Information (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureIncomeTaxesAdditionalInformationDetails Income Taxes - Additional Information (Details) Details 58 false false R59.htm 100590 - Disclosure - Income Taxes - Schedule of Income (Loss) from Continuing Operations Before Income Taxes (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/DisclosureIncomeTaxesScheduleOfIncomeLossFromContinuingOperationsBeforeIncomeTaxesDetails Income Taxes - Schedule of Income (Loss) from Continuing Operations Before Income Taxes (Details) Details 59 false false R60.htm 100600 - Disclosure - Income Taxes - Schedule of Tax Effects of Temporary Differences Give Rise to Significant Portions of Deferred Tax Assets and Deferred Tax Liabilities (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureIncomeTaxesScheduleOfTaxEffectsOfTemporaryDifferencesGiveRiseToSignificantPortionsOfDeferredTaxAssetsAndDeferredTaxLiabilitiesDetails Income Taxes - Schedule of Tax Effects of Temporary Differences Give Rise to Significant Portions of Deferred Tax Assets and Deferred Tax Liabilities (Details) Details 60 false false R61.htm 100610 - Disclosure - Income Taxes - Schedule of Reconciliation of Federal Statutory Income Tax Rate to Effective Income Tax from Continuing Operations (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureIncomeTaxesScheduleOfReconciliationOfFederalStatutoryIncomeTaxRateToEffectiveIncomeTaxFromContinuingOperationsDetails Income Taxes - Schedule of Reconciliation of Federal Statutory Income Tax Rate to Effective Income Tax from Continuing Operations (Details) Details 61 false false R62.htm 100620 - Disclosure - Subsequent Events - Additional Information (Details) Sheet http://aptevotherapeutics.com/20221231/taxonomy/role/Role_DisclosureSubsequentEventsAdditionalInformationDetails Subsequent Events - Additional Information (Details) Details 62 false false All Reports Book All Reports [dq-0542-Deprecated-Concept] Concept PropertyPlantAndEquipmentEstimatedUsefulLives in us-gaap/2022 used in 2 facts was deprecated in us-gaap/2023 as of 2023 and should not be used. apvo-20221231.htm 3291, 3295 [dq-0542-Deprecated-Concept] Concept RevenueFromRelatedParties in us-gaap/2022 used in 5 facts was deprecated in us-gaap/2023 as of 2023 and should not be used. apvo-20221231.htm 3299, 3572 [dq-0542-Deprecated-Concept] Concept LondonInterbankOfferedRateLIBORMember in us-gaap/2022 used in 4 facts was deprecated in us-gaap/2023 as of 2023 and should not be used. apvo-20221231.htm 3533 [ix-0514-Hidden-Fact-Eligible-For-Transform] WARN: 1 fact(s) appearing in ix:hidden were eligible for transformation: dei:CurrentFiscalYearEndDate - apvo-20221231.htm 8 apvo-20221231.htm apvo-20221231.xsd apvo-20221231_cal.xml apvo-20221231_def.xml apvo-20221231_lab.xml apvo-20221231_pre.xml apvo-ex21_1.htm apvo-ex23_1.htm apvo-ex31_1.htm apvo-ex31_2.htm apvo-ex32_1.htm apvo-ex32_2.htm img133665602_0.jpg img133665602_1.jpg img133665602_2.jpg img133665602_3.jpg http://fasb.org/us-gaap/2022 http://xbrl.sec.gov/dei/2022 true true