X0306 4 2022-05-20 0 0001668397 Medpace Holdings, Inc. MEDP 0001777217 Keating Ashley M. C/O MEDPACE HOLDINGS, INC. 5375 MEDPACE WAY CINCINNATI OH 45227 1 0 0 0 STOCK OPTION (RIGHT TO BUY) 133.87 2022-05-20 4 A 0 1903 0 A 2029-05-20 Common Stock 1903 1903 D The option vests on the earlier of (i) the day immediately preceding the date of the first annual meeting of the Issuer following the date of grant, and (ii) the first anniversary of the date of grant, subject to continued service on the board of directors of the Issuer through the vesting date. /s/ Stephen P. Ewald, Attorney-in-Fact for Ashley M. Keating 2022-05-24