Related Party Transactions - Additional Information (Details)		3 Months Ended	6 Months Ended	12 Months Ended
	Jan. 11, 2017 USD ($)	Sep. 30, 2018 Director	Jun. 30, 2017 USD ($)	Dec. 31, 2019 USD ($) Agreement RenewalOption Building	Dec. 31, 2018 USD ($) RenewalOption	Dec. 31, 2017 USD ($)	Dec. 31, 2011 Agreement RenewalOption	Dec. 31, 2016 Parcel	Dec. 31, 2012 USD ($)
Related Party Transaction [Line Items]
Accounts receivable and unbilled, net				$ 1,900,000	$ 3,800,000
Advanced billings				$ 3,000,000.0	400,000
Term of lease				15 years
Number of lease renewal, 10-year option | RenewalOption							1
Lease term upon renewal							10 years
Operating lease cost recognized				$ 13,151,000
Lease expense recognized under 840					9,200,000	$ 7,900,000
Operating lease right-of-use assets				52,152,000	0
Current portion of lease liability				10,977,000
Long-term portion of lease liabilities				45,212,000	0
Lease expiration year							2027
Number of lease agreements | Agreement							2
Lease occupancy year							2012
Deemed landlord liability, long-term portions, under ASC 840				0	24,484,000
Accounts payable due to related parties				200,000	300,000
Cinven
Related Party Transaction [Line Items]
Members of board of directors resigned as result of remaining shares of common stock sold | Director		3
Travel expenses with related party						100,000
Director fees with related party					100,000	100,000
Cinven | Maximum
Related Party Transaction [Line Items]
Travel expenses with related party					100,000
Employee Loans | Prepaid Expenses and Other Current Assets and Other Assets
Related Party Transaction [Line Items]
Employee advances receivables				200,000	$ 200,000
Service Agreements | Coherus Bio Sciences Inc
Related Party Transaction [Line Items]
Amount of investment									$ 2,500,000
Service agreement cancellation notice period					30 days
Revenue with related parties						8,000,000.0
Reimbursed out-of-pocket expenses with related parties						1,300,000
Service Agreements | Xenon
Related Party Transaction [Line Items]
Revenue with related parties			$ 600,000
Reimbursed out-of-pocket revenue with related parties			100,000
Reimbursed out-of-pocket expenses with related parties			$ 100,000
Service Agreements | Cymabay
Related Party Transaction [Line Items]
Revenue with related parties						600,000
Accounts receivable and unbilled, net				1,400,000	$ 2,500,000
Advanced billings				1,600,000
Service Agreements | Cymabay | Revenue Net
Related Party Transaction [Line Items]
Revenue with related parties				13,200,000	10,800,000
Service Agreements | Cymabay | Maximum
Related Party Transaction [Line Items]
Advanced billings					100,000
Service Agreements | LIB
Related Party Transaction [Line Items]
Revenue with related parties						1,400,000
Accounts receivable and unbilled, net				300,000	1,000,000.0
Advanced billings				500,000	300,000
Service Agreements | LIB | Revenue Net
Related Party Transaction [Line Items]
Revenue with related parties				2,000,000.0	3,700,000
Service Agreements | CinRx Pharma and Subsidiaries
Related Party Transaction [Line Items]
Revenue with related parties						400,000
Accounts receivable and unbilled, net				200,000	400,000
Advanced billings				900,000	100,000
Service Agreements | CinRx Pharma and Subsidiaries | Revenue Net
Related Party Transaction [Line Items]
Revenue with related parties				3,700,000	500,000
Service Agreements | The Summit
Related Party Transaction [Line Items]
Expenses incurred				$ 600,000	$ 400,000
Purchase of Real Estate Properties | Chief Executive Officer
Related Party Transaction [Line Items]
Number of parcel in real estate property | Parcel								4
Purchase price of real estate property	$ 400,000
Transaction closed date	Jan. 11, 2017
Leased Real Estate
Related Party Transaction [Line Items]
Number of lease renewal, 10-year option | RenewalOption					2
Lease term upon renewal					10 years
Lease expiration year					2040
Leased Real Estate | Chief Executive Officer
Related Party Transaction [Line Items]
Term of lease				12 years
Lease expiration period				2022-11
Number of lease renewal, 10-year option | RenewalOption				1
Lease term upon renewal				10 years
Lease expense recognized under 840					$ 2,200,000	2,100,000
Leased Real Estate | Chief Executive Officer | Direct Service Costs, Excluding Depreciation and Amortization, and Selling, General and Administrative
Related Party Transaction [Line Items]
Operating lease cost recognized				$ 2,000,000.0
Leased Real Estate | Chief Executive Officer And Immediate Family
Related Party Transaction [Line Items]
Term of lease				15 years
Number of lease renewal, 10-year option | RenewalOption				1
Lease term upon renewal				10 years
Lease expiration year				2027
Number of lease agreements | Agreement				2
Number of buildings | Building				2
Lease occupancy year				2012
Related party capital lease payments under ASC 840					3,800,000	3,800,000
Deemed landlord liability, current, under ASC 840					2,100,000
Deemed landlord liability, long-term portions, under ASC 840					24,500,000
Leased Real Estate | Chief Executive Officer And Immediate Family | Direct Service Costs, Excluding Depreciation and Amortization, and Selling, General and Administrative
Related Party Transaction [Line Items]
Operating lease cost recognized				$ 3,600,000
Leased Real Estate | Operating Lease Right-of-Use Assets | Chief Executive Officer
Related Party Transaction [Line Items]
Operating lease right-of-use assets				5,300,000
Leased Real Estate | Operating Lease Right-of-Use Assets | Chief Executive Officer And Immediate Family
Related Party Transaction [Line Items]
Operating lease right-of-use assets				21,900,000
Leased Real Estate | Other Current Liabilities | Chief Executive Officer
Related Party Transaction [Line Items]
Current portion of lease liability				1,800,000
Leased Real Estate | Other Current Liabilities | Chief Executive Officer And Immediate Family
Related Party Transaction [Line Items]
Current portion of lease liability				2,300,000
Leased Real Estate | Operating Lease Liabilities | Chief Executive Officer
Related Party Transaction [Line Items]
Long-term portion of lease liabilities				3,500,000
Leased Real Estate | Operating Lease Liabilities | Chief Executive Officer And Immediate Family
Related Party Transaction [Line Items]
Long-term portion of lease liabilities				19,700,000
Leased Real Estate | Property and Equipment, Net | Chief Executive Officer And Immediate Family | Building
Related Party Transaction [Line Items]
Deemed assets, net, under ASC 840					14,600,000
Travel Services | Chief Executive Officer
Related Party Transaction [Line Items]
Travel expenses with related party				1,200,000	1,300,000	$ 1,100,000
Accounts payable due to related parties					$ 200,000
Travel Services | Chief Executive Officer | Maximum
Related Party Transaction [Line Items]
Accounts payable due to related parties				$ 100,000