CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Dec. 31, 2017	Dec. 31, 2016
Current assets:
Cash and cash equivalents	$ 26,485	$ 37,099
Restricted cash	7	308
Accounts receivable and unbilled, net (includes $1.0 million and $2.3 million with related parties at December 31, 2017 and 2016, respectively)	83,079	79,767
Prepaid expenses and other current assets	20,400	16,074
Total current assets	129,971	133,248
Property and equipment, net	48,739	43,805
Goodwill	660,981	660,981
Intangible assets, net	98,740	136,071
Deferred income taxes	6,343	97
Other assets	5,943	4,903
Total assets	950,717	979,105
Current liabilities:
Accounts payable	16,674	10,911
Accrued expenses	23,673	24,417
Pre-funded study costs (includes $1.0 million and $3.9 million with related parties at December 31, 2017 and 2016, respectively)	57,406	51,948
Advanced billings (includes $1.7 million and $7.6 million with related parties at December 31, 2017 and 2016, respectively)	73,756	65,668
Current portion of long-term debt	16,500	12,375
Other current liabilities	4,697	3,284
Total current liabilities	192,706	168,603
Long-term debt, net, less current portion	205,111	151,267
Deemed landlord liability, less current portion	26,602	28,527
Deferred income tax liability	560	12,030
Deferred credit	11,468	0
Other long-term liabilities	10,740	7,968
Total liabilities	447,187	368,395
Commitments and contingencies (see Note 9)	0	0
Shareholders’ equity:
Preferred stock - $0.01 par-value; 5,000,000 shares authorized; 0 shares issued and outstanding at December 31, 2017 and 2016, respectively	0	0
Common stock - $0.01 par-value; 250,000,000 shares authorized at December 31, 2017 and 2016, respectively; 35,466,510 and 40,662,856 shares issued and outstanding at December 31, 2017 and 2016, respectively	355	407
Treasury stock - 200,000 shares at December 31, 2017	(6,030)	0
Additional paid-in capital	630,341	623,629
Accumulated deficit	(120,402)	(9,584)
Accumulated other comprehensive loss	(734)	(3,742)
Total shareholders’ equity	503,530	610,710
Total liabilities and shareholders’ equity	$ 950,717	$ 979,105