CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (UNAUDITED) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2017	Mar. 31, 2016
CASH FLOWS FROM OPERATING ACTIVITIES:
Net income	$ 8,447	$ 3,448
Adjustments to reconcile net income to net cash (used in) provided by operating activities:
Depreciation	2,130	1,773
Amortization	9,448	12,668
Stock-based compensation expense	1,034	1,009
Amortization of debt issuance costs and discount	165	672
Deferred income tax benefit	(410)	(310)
Other	(252)	46
Changes in assets and liabilities:
Accounts receivable and unbilled, net	(2,292)	(9,927)
Prepaid expenses and other current assets	(247)	(1,264)
Accounts payable	(1,331)	(2,027)
Accrued expenses	(10,508)	(5,004)
Pre-funded study costs	(3,497)	1,305
Advanced billings	(5,246)	9,669
Other assets and liabilities, net	1,884	567
Net cash (used in) provided by operating activities	(675)	12,625
CASH FLOWS FROM INVESTING ACTIVITIES:
Property and equipment expenditures	(4,374)	(3,456)
Other	16	32
Net cash used in investing activities	(4,358)	(3,424)
CASH FLOWS FROM FINANCING ACTIVITIES:
Proceeds from stock option exercises	193	7
Payment of debt	(3,094)	(18)
Payment of deemed landlord liability	(404)	(369)
Net cash used in financing activities	(3,305)	(380)
EFFECT OF EXCHANGE RATES ON CASH, CASH EQUIVALENTS, AND RESTRICTED CASH	540	384
(DECREASE) INCREASE IN CASH, CASH EQUIVALENTS, AND RESTRICTED CASH	(7,798)	9,205
CASH, CASH EQUIVALENTS, AND RESTRICTED CASH — Beginning of period	37,407	17,737
CASH, CASH EQUIVALENTS, AND RESTRICTED CASH — End of period	$ 29,609	$ 26,942