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Contract with customer, liability, current with related parties.

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Lease expiration month and year.

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Lease expiration year.

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Lease occupancy year.

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Lease Term Reassessment Description

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Number of buildings.

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Number of lease agreements.

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Number of lease renewal options.

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Amount for accounts payable to related parties. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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For an unclassified balance sheet, amounts due from an Entity employee, not to include stockholders or officers.

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Term of lessee's operating lease renewal, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

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Term of lessee's operating lease, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

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Amount of single lease cost, calculated by allocation of remaining cost of lease over remaining lease term. Includes, but is not limited to, single lease cost, after impairment of right-of-use asset, calculated by amortization of remaining right-of-use asset and accretion of lease liability.

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Present value of lessee's discounted obligation for lease payments from operating lease, classified as current.

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Present value of lessee's discounted obligation for lease payments from operating lease, classified as noncurrent.

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Amount of lessee's right to use underlying asset under operating lease.

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Expenses recognized resulting from transactions (excluding transactions that are eliminated in consolidated or combined financial statements) with related party.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Amount of revenue, fees and commissions earned from transactions between (a) a parent company and its subsidiaries; (b) subsidiaries of a common parent; (c) an entity and trusts for the benefit of employees, for example, but not limited to, pension and profit-sharing trusts that are managed by or under the trusteeship of the entity's management; (d) an entity and its principal, owners, management, or members of their immediate families; and (e) affiliates.

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Expenses incurred for travel and entertainment during the period.

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Related Party Transactions - Additional Information (Details) $ in Thousands	12 Months Ended
	Dec. 31, 2021 USD ($) Building Agreement RenewalOption	Dec. 31, 2020 USD ($)	Dec. 31, 2019 USD ($)	Jan. 01, 2019 USD ($)
Related Party Transaction [Line Items]
Advanced billings	$ 8,300	$ 6,500
Accounts receivable and unbilled, net	2,700	2,600
Operating lease cost recognized	23,873	19,842
Operating lease right-of-use assets	129,558	113,809		$ 51,854
Current portion of lease liability	16,276	15,890
Long-term portion of lease liabilities	130,965	115,143		$ 45,294
Accounts payable	300	200
Employee Loans \| Prepaid Expenses and Other Current Assets and Other Assets
Related Party Transaction [Line Items]
Employee advances receivables	200	200
Service Agreement \| Cymabay \| Revenue Net
Related Party Transaction [Line Items]
Revenue with related parties			$ 13,200
Service Agreement \| LIB
Related Party Transaction [Line Items]
Advanced billings	2,900	700
Accounts receivable and unbilled, net	500	300
Service Agreement \| LIB \| Revenue Net
Related Party Transaction [Line Items]
Revenue with related parties	11,800	2,600	2,000
Service Agreement \| CinRx Pharma and Subsidiaries
Related Party Transaction [Line Items]
Advanced billings	5,400	5,800
Accounts receivable and unbilled, net	2,100	2,200
Service Agreement \| CinRx Pharma and Subsidiaries \| Revenue Net
Related Party Transaction [Line Items]
Revenue with related parties	22,700	13,200	3,700
Service Agreement \| The Summit
Related Party Transaction [Line Items]
Expenses incurred	$ 300	400	600
Leased Real Estate \| Chief Executive Officer
Related Party Transaction [Line Items]
Term of lease	12 years
Lease expiration period	2022-11
Number of lease renewal, 10-year option \| RenewalOption	1
Lease term upon renewal	10 years
Lease term reassessment Description	In the third quarter of fiscal year 2021, the Company accounted for the renewal option, as it became reasonably certain it would be exercised per the agreement, by extending the lease term through November 2032.
Leased Real Estate \| Chief Executive Officer \| Direct Costs and Selling General And Administrative
Related Party Transaction [Line Items]
Operating lease cost recognized	$ 2,100	2,000	2,000
Leased Real Estate \| Chief Executive Officer And Immediate Family \| Office Space
Related Party Transaction [Line Items]
Number of lease renewal, 10-year option \| RenewalOption	2
Lease term upon renewal	10 years
Lease expiration year	2040
Number of lease agreements \| Agreement	1
Leased Real Estate \| Chief Executive Officer And Immediate Family \| Building
Related Party Transaction [Line Items]
Number of lease renewal, 10-year option \| RenewalOption	1
Lease term upon renewal	10 years
Lease expiration year	2027
Number of lease agreements \| Agreement	2
Number of buildings \| Building	2
Lease occupancy year	2012
Leased Real Estate \| Chief Executive Officer And Immediate Family \| Direct Costs and Selling General And Administrative \| Office Space
Related Party Transaction [Line Items]
Operating lease cost recognized	$ 5,700	3,600
Leased Real Estate \| Chief Executive Officer And Immediate Family \| Direct Costs and Selling General And Administrative \| Building
Related Party Transaction [Line Items]
Operating lease cost recognized	3,600	3,600	3,600
Leased Real Estate \| Operating Lease Right-of-Use Assets \| Chief Executive Officer
Related Party Transaction [Line Items]
Operating lease right-of-use assets	19,700	3,500
Leased Real Estate \| Operating Lease Right-of-Use Assets \| Chief Executive Officer And Immediate Family \| Office Space
Related Party Transaction [Line Items]
Operating lease right-of-use assets	55,100	56,600
Leased Real Estate \| Operating Lease Right-of-Use Assets \| Chief Executive Officer And Immediate Family \| Building
Related Party Transaction [Line Items]
Operating lease right-of-use assets	17,200	19,700
Leased Real Estate \| Other Current Liabilities \| Chief Executive Officer
Related Party Transaction [Line Items]
Current portion of lease liability	1,500	1,900
Leased Real Estate \| Other Current Liabilities \| Chief Executive Officer And Immediate Family \| Office Space
Related Party Transaction [Line Items]
Current portion of lease liability	900	700
Leased Real Estate \| Other Current Liabilities \| Chief Executive Officer And Immediate Family \| Building
Related Party Transaction [Line Items]
Current portion of lease liability	2,600	2,400
Leased Real Estate \| Operating Lease Liabilities \| Chief Executive Officer
Related Party Transaction [Line Items]
Long-term portion of lease liabilities	18,300	1,600
Leased Real Estate \| Operating Lease Liabilities \| Chief Executive Officer And Immediate Family \| Office Space
Related Party Transaction [Line Items]
Long-term portion of lease liabilities	65,900	66,800
Leased Real Estate \| Operating Lease Liabilities \| Chief Executive Officer And Immediate Family \| Building
Related Party Transaction [Line Items]
Long-term portion of lease liabilities	14,600	17,200
Travel Services
Related Party Transaction [Line Items]
Accounts payable	200
Travel Services \| Maximum
Related Party Transaction [Line Items]
Accounts payable		100
Travel Services \| Chief Executive Officer
Related Party Transaction [Line Items]
Travel expenses with related party	$ 1,300	$ 700	$ 1,200