X0306 4 2018-09-19 0 0001668397 Medpace Holdings, Inc. MEDP 0001622058 Troendle August J. C/O MEDPACE HOLDINGS, INC. 5375 MEDPACE WAY CINCINNATI OH 45227 1 1 1 0 President & CEO Common Stock 2018-09-19 4 S 0 61141 60.20 D 9084369 I By Medpace Investors, LLC Common Stock 2018-09-20 4 S 0 53842 58.29 D 9030527 I By Medpace Investors, LLC Common Stock 351851 D Common Stock 10000 I By Son The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by Medpace Investors, LLC ("MPI") on August 20, 2018. The reported price is a weighted average price. These shares were sold in multiple transactions at prices ranging from $58.00 to $64.47. The Reporting Person undertakes to provide full pricing information to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission upon request. The Reporting Person is the sole manager and controlling unit holder of MPI and has sole voting and investment control with respect to the shares held by MPI. The Reporting Person may be deemed to indirectly beneficially own the securities of the Issuer held by MPI but disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein. The reported price is a weighted average price. These shares were sold in multiple transactions at prices ranging from $58.00 to $58.74. The Reporting Person undertakes to provide full pricing information to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission upon request. /s/ Stephen P. Ewald, Attorney-in-Fact for August J. Troendle 2018-09-21