X0609 4 2026-08-19 0001668397 Medpace Holdings, Inc. MEDP 0001622058 Troendle August J. false C/O MEDPACE HOLDINGS, INC. 5375 MEDPACE WAY CINCINNATI OH 45227 true true true false President & CEO false Common Stock 2026-08-19 4 S false 15609 606.47 D 588369 D Common Stock 2026-08-20 4 S false 27174 618.79 D 561195 D Common Stock 4733019 I By Medpace Investors, LLC The transactions reported on this Form 4 were effected pursuant to a limit order placed by the Reporting Person during an open window period. The reported price is a weighted average price. These shares were sold in multiple transactions ranging from $601.29 to $611.42. The Reporting Person undertakes to provide full pricing information to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission upon request. The reported price is a weighted average price. These shares were sold in multiple transactions ranging from $606.20 to $626.51. The Reporting Person undertakes to provide full pricing information to the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission upon request. The Reporting Person is the sole manager and controlling unit holder of Medpace Investors, LLC ("MPI") and has sole voting and investment control with respect to the securities held by MPI. The Reporting Person may be deemed to indirectly beneficially own the securities of the Issuer held by MPI but disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein. /s/Stephen P. Ewald, Attorney-in-Fact for August J. Troendle 2026-08-21