X0508 4 2023-11-29 0001668397 Medpace Holdings, Inc. MEDP 0001524599 Medpace Investors, LLC C/O MEDPACE HOLDINGS, INC. 5375 MEDPACE WAY CINCINNATI OH 45227 true false Common Stock 2023-11-29 4 S 0 3167 272.87 D 5639947 D Common Stock 2023-11-29 4 S 0 18090 272.62 D 5621857 D Common Stock 2023-11-30 4 S 0 7871 272.18 D 5613986 D Common Stock 2023-12-01 4 S 0 24039 273.26 D 5589947 D The transactions reported on this Form 4 were effected pursuant to a limit order placed by the Reporting Person during an open window period. The reported price is a weighted average price. These shares were sold in multiple transactions ranging from $272.06 to $273.955. The Reporting Person undertakes to provide full pricing information to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission upon request. The reported price is a weighted average price. These shares were sold in multiple transactions ranging from $272.00 to $274.415. The Reporting Person undertakes to provide full pricing information to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission upon request. The reported price is a weighted average price. These shares were sold in multiple transactions ranging from $272.00 to $273.75. The Reporting Person undertakes to provide full pricing information to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission upon request. The reported price is a weighted average price. These shares were sold in multiple transactions ranging from $272.00 to $274.565. The Reporting Person undertakes to provide full pricing information to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission upon request. /s/ Stephen P. Ewald, Authorized Signatory for Medpace Investors, LLC 2023-12-01