X0508 4/A 2022-03-25 2022-03-29 0001668243 UroGen Pharma Ltd. URGN 0001920163 Kim Dong 400 ALEXANDER PARK DRIVE PRINCETON NJ 08540 1 Chief Financial Officer 0 Stock Option (right to buy) 8.61 2022-03-25 4 A 0 20000 0 A 2032-03-25 Ordinary Shares 20000 20000 D One third of the shares underlying the stock option will vest on each of March 25, 2023, March 25, 2024 and March 25, 2025. This amendment corrects and restates the number of derivative securities acquired reported in the original Form 4 filed on March 29, 2022. This amendment corrects and restates the expiration date reported in the original Form 4 filed on March 29, 2022. This amendment corrects and restates the amount of securities underlying derivative security reported in the original Form 4 filed on March 29, 2022. This amendment corrects and restates the number of derivative securities beneficially owned following reported transaction reported in the original Form 4 filed on March 29, 2022. /s/ Jason D. Smith, Attorney-in-Fact 2024-02-12