X0306 4 2019-12-04 0 0001668243 UroGen Pharma Ltd. URGN 0001763581 Schoenberg Mark C/O UROGEN PHARMA LTD. 499 PARK AVENUE NEW YORK CITY NY 10022 0 1 0 0 Chief Medical Officer Ordinary Shares 2019-12-04 4 M 0 1042 A 9009 D Ordinary Shares 2019-12-04 4 F 0 343 31.69 D 8666 D Restricted Stock Units (RSUs) 2019-12-04 4 M 0 1042 0.00 D Ordinary Shares 1042 4167 D Each restricted stock unit represents a contingent right to receive one ordinary share of the Issuer. Represents shares sold to satisfy withholding tax obligations upon the settlement of restricted stock units. The transaction reported herein was matchable under Section 16(b) of the Securities and Exchange Act of 1934, to the extent of 343 shares, with the reporting person's purchase of 1,960 ordinary shares of the Issuer at a price of $28.17 per share on November 19, 2019. The reporting person has paid to the Issuer $1,207.36, representing the full amount of the profit realized in connection with the short-swing transaction. On December 7, 2017, the reporting person was granted restricted stock units ("RSUs") representing 12,500 ordinary shares. 1/3rd of the RSUs vested on December 4, 2018, with the balance vesting in equal quarterly installments thereafter over a period of three years. /s/ Peter Pfreundschuh, Attorney-in-Fact 2019-12-05