X0306 4 2019-03-21 0 0001668243 UroGen Pharma Ltd. URGN 0001763581 Schoenberg Mark C/O UROGEN PHARMA LTD. 9 HA?TA?ASIYA STREET RA?ANANA L3 4365007 ISRAEL 0 1 0 0 Chief Medical Officer Ordinary Shares 2019-03-21 4 P 0 272 37.009 A 4610 D The reporting person's purchase of Ordinary Shares of the Issuer reported herein was matchable under Section 16(b) of the Securities Exchange Act of 1934 with the reporting person's sale of 272 Ordinary Shares of the Issuer at a price of $37.30 per share on March 6, 2019. The reporting person has agreed to pay to the Issuer $79.15, representing the full amount of the profit realized in connection with the short-swing transaction. /s/ Peter Pfreundschuh, Attorney-in-Fact 2019-03-21