X0306 4 2019-02-14 0 0001668243 UroGen Pharma Ltd. URGN 0001764139 Mullennix Stephen C/O UROGEN PHARMA LTD. 9 HA?TA?ASIYA STREET RA?ANANA L3 4365007 ISRAEL 0 1 0 0 Chief Operating Officer Ordinary Shares 2019-02-14 4 M 0 7034 A 7034 D Ordinary Shares 2019-02-14 4 S 0 2804 37.30 D 4230 D Restricted Stock Units 2019-02-14 4 M 0 7034 0.00 D Ordinary Shares 7034 14073 D Each restricted stock unit represents a contingent right to receive one ordinary share of the Issuer. Represents shares sold to satisfy withholding tax obligations upon the settlement of restricted stock units. The reporting person was granted restricted stock units ("RSUs") on March 7, 2018, June 4, 2018 and October 28, 2018 representing 21,107 ordinary shares in the aggregate. 1/3rd of the RSUs vested on February 14, 2019 (with the issuance of the underlying ordinary shares delayed until March 5, 2019), with the balance vesting in equal quarterly installments thereafter over a period of two years. /s/ Peter Pfreundschuh, Attorney-in-Fact 2019-03-07