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Share Capital - Schedule of Effect of Share-Based Compensation on Statements of Operations (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]    
Share-based compensation $ 4,541 $ 297
Research and Development Expenses    
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]    
Share-based compensation 2,473 170
General and Administrative Expenses    
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]    
Share-based compensation $ 2,068 $ 127