X0306 4 2018-05-29 0 0001668234 NEXPOINT HEALTHCARE OPPORTUNITIES FUND NONE 0001228922 DONDERO JAMES D 300 CRESCENT COURT, SUITE 700 DALLAS TX 75201 0 1 0 0 See Remarks Class A Shares of Beneficial Interest 2018-05-29 4 P 0 2500 20.00 A 2500 I See Footnote Class C Shares of Beneficial Interest 2018-05-29 4 P 0 2500 20.00 A 2500 I See Footnote Class Z Shares of Beneficial Interest 2018-05-29 4 P 0 50 20.00 A 50 I See Footnote These shares are held by NexPoint Advisors, L.P. ("NexPoint"). The Reporting Person is the President of NexPoint and sole member of NexPoint Advisors GP, LLC, NexPoint's general partner, and may be deemed to be an indirect beneficial owner of shares held by NexPoint. The Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein. President (Principal Executive Officer) /s/ James D. Dondero 2018-05-31