X0508 4 2025-03-05 0001858848 Tenaya Therapeutics, Inc. TNYA 0001790965 COLUMN GROUP III GP, LP 1 LETTERMAN DR BLDG. D, STE. DM-900 SAN FRANCISCO CA 94129 false false true false 0001668159 COLUMN GROUP III, LP 1 LETTERMAN DRIVE BLDG. D, STE DM-900 SAN FRANCISCO CA 94129 false false true false 0001668085 COLUMN GROUP III-A, LP 1 LETTERMAN DR BLDG. D, STE, DM-900 SAN FRANCISCO CA 94129 false false true false 0001931825 Column Group Opportunity III, LP 1 LETTERMAN DRIVE BUILDING D, SUITE DM-900 SAN FRANCISCO CA 94129 false false true false 0001932874 Column Group Opportunity III GP, LP 1 LETTERMAN DRIVE BUILDING D, SUITE DM-900 SAN FRANCISCO CA 94129 false false true false 0001932445 TCG Opportunity III GP, LLC 1 LETTERMAN DRIVE BUILDING D, SUITE DM-900 SAN FRANCISCO CA 94129 false false true false false Common Stock 2025-03-05 4 P false 35714284 0.7 A 49313559 I See Footnote Common Stock 4414720 I See Footnote Common Stock 4985570 I See Footnote Series A Warrant (right to buy) 0.8 2025-03-05 4 P false 35714284 A 2030-03-04 Common Stock 35714284 35714284 I See Footnote Series B Warrant (right to buy) 0.7 2025-03-05 4 P false 17857142 A 2026-06-30 Common Stock 17857142 17857142 I See Footnote Pursuant to an underwritten public offering, The Column Group Opportunity III, LP ("TCG Opportunity III LP") purchased units (the "Units") at a price per Unit of $0.70 per Unit. Each Unit consists of (a) one share of the Issuer's common stock, par value $0.0001 per share (the "Common Stock", and such shares, the "Shares"), (b) one Series A warrant to purchase one share of Common Stock at an exercise price of $0.80 per share which will expire five years from the date of issuance (a "Series A Warrant") and (c) one half of a Series B warrant to purchase a share of Common Stock at an exercise price of $0.70 per share that will expire on June 30, 2026 (a "Series B Warrant"). The securities are directly held by TCG Opportunity III LP. The Column Group Opportunity III GP, LP ("TCG Opportunity III GP LP") is the general partner of TCG Opportunity III LP and may be deemed to have voting, investment and dispositive power with respect to these securities. TCG Opportunity III GP, LLC ("TCG Opportunity III GP LLC") is the general partner of TCG Opportunity III GP LP and the ultimate general partner of TCG Opportunity III LP and may be deemed to have voting, investment and dispositive power with respect to these securities. The managing members of TCG Opportunity III GP LLC are David Goeddel, a member of the Issuer's board of directors, Peter Svennilson and Tim Kutzkey (collectively, the "Managing Partners"). (Continued from Footnote 2) The Managing Partners may be deemed to share voting, investment and dispositive power with respect to such securities. TCG Opportunity III GP LP, TCG Opportunity III GP LLC and each of the Managing Partners disclaim beneficial ownership of these securities, except to the extent of their respective pecuniary interest in such securities. The securities are directly held by The Column Group III, LP ("TCG III LP"). The Column Group III GP, LP ("TCG III GP") is the general partner of TCG III LP and may be deemed to have voting, investment and dispositive power with respect to these securities. The managing partners of TCG III GP are the Managing Partners. The Managing Partners may be deemed to share voting, investment and dispositive power with respect to such shares. TCG III GP and each of the Managing Partners disclaim beneficial ownership of these shares, except to the extent of their respective pecuniary interest in such shares. The securities are directly held by The Column Group III-A, LP ("TCG III-A LP"). TCG III GP is the general partner of TCG III-A LP and may be deemed to have voting, investment and dispositive power with respect to these securities. The managing partners of TCG III GP are the Managing Partners. The Managing Partners may be deemed to share voting, investment and dispositive power with respect to such shares. TCG III GP and each of the Managing Partners disclaim beneficial ownership of these shares, except to the extent of their respective pecuniary interest in such shares. Each Series A Warrant is immediately exercisable (subject to certain beneficial ownership limitations). Each Series B Warrant is immediately exercisable (subject to certain beneficial ownership limitations). The Column Group III GP, LP /s/James Evangelista, Attorney-in-Fact 2025-03-07 The Column Group III, LP by The Column Group III GP, LP, its general partner /s/ James Evangelista Attorney-in-Fact 2025-03-07 The Column Group III-A, LP. by The Column Group III GP, LP, its general partner /s/ James Evangelista Attorney-in-Fact 2025-03-07 /s/ James Evangelista, as Attorney-in-Fact for The Column Group Opportunity III LP 2025-03-07 /s/ James Evangelista, as Attorney-in-Fact for The Column Group Opportunity III GP LP 2025-03-07 /s/ James Evangelista, as Attorney-in-Fact for TCG Opportunity III GP, LLC 2025-03-07