License Agreements (Details) $ in Thousands		12 Months Ended
	Apr. 05, 2016 USD ($) shares	Dec. 31, 2022 product	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)	Dec. 31, 2017 USD ($)	Dec. 31, 2016 USD ($)
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Payment for achievement of clinical and regulatory milestones			$ 300	$ 50
MGH | License Agreement
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Initial license payment						$ 100
Reimbursement of prior patent prosecution expenses					$ 300
Sale of stock, number of shares issued in transaction (in shares) | shares	358,674
Number of products | product		3
Clinical and regulatory milestone payments	$ 8,600
Commercial milestone payments	$ 18,000
Royalty rate, maximum reduction	50.00%
Expiration period	10 years	10 years