<SEC-DOCUMENT>0001636282-25-000069-index.html : 20250602
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<ACCEPTANCE-DATETIME>20250602163953
ACCESSION NUMBER:		0001636282-25-000069
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20250529
FILED AS OF DATE:		20250602
DATE AS OF CHANGE:		20250602

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Fairmount Healthcare Fund II L.P.
		CENTRAL INDEX KEY:			0001769651
		ORGANIZATION NAME:           	
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37722
		FILM NUMBER:		251015624

	BUSINESS ADDRESS:	
		STREET 1:		200 BARR HARBOR DRIVE
		STREET 2:		SUITE 400
		CITY:			WEST CONSHOHOCKEN
		STATE:			PA
		ZIP:			19428
		BUSINESS PHONE:		(267) 760-4066

	MAIL ADDRESS:	
		STREET 1:		200 BARR HARBOR DRIVE
		STREET 2:		SUITE 400
		CITY:			WEST CONSHOHOCKEN
		STATE:			PA
		ZIP:			19428

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Harwin Peter Evan
		CENTRAL INDEX KEY:			0001663607
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37722
		FILM NUMBER:		251015626

	MAIL ADDRESS:	
		STREET 1:		200 BARR HARBOR DRIVE
		STREET 2:		SUITE 400
		CITY:			WEST CONSHOHOCKEN
		STATE:			PA
		ZIP:			19428

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Kiselak Tomas
		CENTRAL INDEX KEY:			0001830177
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37722
		FILM NUMBER:		251015625

	MAIL ADDRESS:	
		STREET 1:		200 BARR HARBOR DRIVE
		STREET 2:		SUITE 400
		CITY:			WEST CONSHOHOCKEN
		STATE:			PA
		ZIP:			19428

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Fairmount Funds Management LLC
		CENTRAL INDEX KEY:			0001802528
		ORGANIZATION NAME:           	
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37722
		FILM NUMBER:		251015627

	BUSINESS ADDRESS:	
		STREET 1:		200 BARR HARBOR DRIVE
		STREET 2:		SUITE 400
		CITY:			WEST CONSHOHOCKEN
		STATE:			PA
		ZIP:			19428
		BUSINESS PHONE:		267-262-5300

	MAIL ADDRESS:	
		STREET 1:		200 BARR HARBOR DRIVE
		STREET 2:		SUITE 400
		CITY:			WEST CONSHOHOCKEN
		STATE:			PA
		ZIP:			19428

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Spyre Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001636282
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				464312787
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		221 CRESCENT STREET
		STREET 2:		BUILDING 23, SUITE 105
		CITY:			WALTHAM
		STATE:			MA
		ZIP:			02453
		BUSINESS PHONE:		6176515940

	MAIL ADDRESS:	
		STREET 1:		221 CRESCENT STREET
		STREET 2:		BUILDING 23, SUITE 105
		CITY:			WALTHAM
		STATE:			MA
		ZIP:			02453

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Aeglea BioTherapeutics, Inc.
		DATE OF NAME CHANGE:	20150311
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