<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2016-01-06</periodOfReport>

    <noSecuritiesOwned>1</noSecuritiesOwned>

    <issuer>
        <issuerCik>0000837852</issuerCik>
        <issuerName>YOU ON DEMAND HOLDINGS, INC.</issuerName>
        <issuerTradingSymbol>YOD</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001663203</rptOwnerCik>
            <rptOwnerName>Fan Jian Ren</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>EASTERN FANGZHENG ROAD</rptOwnerStreet1>
            <rptOwnerStreet2>SOUTHERN DONGYING VILLAGE, HANCUNHE TOWN</rptOwnerStreet2>
            <rptOwnerCity>FANGSHAN DIST, BEIJING</rptOwnerCity>
            <rptOwnerState>F4</rptOwnerState>
            <rptOwnerZipCode>102423</rptOwnerZipCode>
            <rptOwnerStateDescription>CHINA</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle></officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <remarks>Exhibit 24.1 - Power of Attorney (filed herewith)</remarks>

    <ownerSignature>
        <signatureName>/s/ William Haddad, Attorney-in-Fact for Jian Ren Fan</signatureName>
        <signatureDate>2016-01-13</signatureDate>
    </ownerSignature>
</ownershipDocument>
