X0508 4 2023-09-01 0 0001662774 Quince Therapeutics, Inc. QNCX 0001624830 Ryan Charles S. C/O QUINCE THERAPEUTICS, INC. 601 GATEWAY BOULEVARD, SUITE 1250 SOUTH SAN FRANCISCO CA 94080 0 1 0 0 President 0 Employee Stock Option (right to buy) 1.30 2023-09-01 4 A 0 545000 0.00 A 2033-08-31 Common Stock 545000 545000 D 25% of the shares subject to the option will vest one year after the date of the grant of September 1, 2023 and the remaining shares will vest in equal monthly installments over the following three years thereafter. /s/ Brendan Hannah, Attorney-in-Fact for Charles S. Ryan, Ph.D. 2023-09-06