<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
<headerData>
<submissionType>SCHEDULE 13G/A</submissionType>
<previousAccessionNumber>0001140361-23-057682</previousAccessionNumber>
<filerInfo>
<filer>
<filerCredentials>
<cik>0001559515</cik>
<ccc>XXXXXXXX</ccc>
</filerCredentials>
</filer>
<liveTestFlag>LIVE</liveTestFlag>



</filerInfo>
</headerData>
<formData>
<coverPageHeader>
<amendmentNo>2</amendmentNo>
<securitiesClassTitle>Common Stock, par value $0.001 per share</securitiesClassTitle>
<eventDateRequiresFilingThisStatement>07/07/2025</eventDateRequiresFilingThisStatement>
<issuerInfo>
<issuerCik>0001662774</issuerCik>
<issuerName>Quince Therapeutics, Inc.</issuerName>
<issuerCusip>22053A107</issuerCusip>
<issuerPrincipalExecutiveOfficeAddress>
<com:street1>611 Gateway Boulevard, Suite 273</com:street1>
<com:city>South San Francisco</com:city>
<com:stateOrCountry>CA</com:stateOrCountry>
<com:zipCode>94080</com:zipCode>
</issuerPrincipalExecutiveOfficeAddress>
</issuerInfo>
<designateRulesPursuantThisScheduleFiled>
<designateRulePursuantThisScheduleFiled>Rule 13d-1(c)</designateRulePursuantThisScheduleFiled>
</designateRulesPursuantThisScheduleFiled>
</coverPageHeader>
<coverPageHeaderReportingPersonDetails>

<reportingPersonName>Genextra S.p.A.</reportingPersonName>
<citizenshipOrOrganization>L6</citizenshipOrOrganization>
<reportingPersonBeneficiallyOwnedNumberOfShares>
<soleVotingPower>0</soleVotingPower>
<sharedVotingPower>0</sharedVotingPower>
<soleDispositivePower>0</soleDispositivePower>
<sharedDispositivePower>0</sharedDispositivePower>
</reportingPersonBeneficiallyOwnedNumberOfShares>
<reportingPersonBeneficiallyOwnedAggregateNumberOfShares>0</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
<aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
<classPercent>0</classPercent>
<typeOfReportingPerson>OO</typeOfReportingPerson>
</coverPageHeaderReportingPersonDetails>
<coverPageHeaderReportingPersonDetails>

<reportingPersonName>Francesco Micheli</reportingPersonName>
<citizenshipOrOrganization>L6</citizenshipOrOrganization>
<reportingPersonBeneficiallyOwnedNumberOfShares>
<soleVotingPower>0</soleVotingPower>
<sharedVotingPower>0</sharedVotingPower>
<soleDispositivePower>0</soleDispositivePower>
<sharedDispositivePower>0</sharedDispositivePower>
</reportingPersonBeneficiallyOwnedNumberOfShares>
<reportingPersonBeneficiallyOwnedAggregateNumberOfShares>0</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
<aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
<classPercent>0</classPercent>
<typeOfReportingPerson>IN</typeOfReportingPerson>
</coverPageHeaderReportingPersonDetails>
<coverPageHeaderReportingPersonDetails>

<reportingPersonName>Matteo Bruno Renzulli</reportingPersonName>
<citizenshipOrOrganization>L6</citizenshipOrOrganization>
<reportingPersonBeneficiallyOwnedNumberOfShares>
<soleVotingPower>0</soleVotingPower>
<sharedVotingPower>0</sharedVotingPower>
<soleDispositivePower>0</soleDispositivePower>
<sharedDispositivePower>0</sharedDispositivePower>
</reportingPersonBeneficiallyOwnedNumberOfShares>
<reportingPersonBeneficiallyOwnedAggregateNumberOfShares>0</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
<aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
<classPercent>0</classPercent>
<typeOfReportingPerson>IN</typeOfReportingPerson>
</coverPageHeaderReportingPersonDetails>
<items>
<item1>
<issuerName>Quince Therapeutics, Inc.</issuerName>
<issuerPrincipalExecutiveOfficeAddress>611 Gateway Boulevard, Suite 273, South San Francisco, California, 94080</issuerPrincipalExecutiveOfficeAddress>
</item1>
<item2>
<filingPersonName>This Schedule 13G is filed jointly by each of the following persons (collectively, the "Reporting Persons") pursuant to a joint filing agreement:  &#13;
(1) Genextra S.p.A.&#13;
(2) Francesco Micheli&#13;
(3) Matteo Bruno Renzulli</filingPersonName>
<principalBusinessOfficeOrResidenceAddress>Via Giovanni De Grassi, 11&#13;
20123 Milano&#13;
Italy</principalBusinessOfficeOrResidenceAddress>
<citizenship>Genextra S.p.A. is formed under Italian law. Francesco Micheli is an Italian citizen. Matteo Bruno Renzulli is an Italian citizen.</citizenship>
</item2>
<item4>
<amountBeneficiallyOwned>0</amountBeneficiallyOwned>
<classPercent>0</classPercent>
<numberOfSharesPersonHas>
<solePowerOrDirectToVote>0</solePowerOrDirectToVote>
<sharedPowerOrDirectToVote>0</sharedPowerOrDirectToVote>
<solePowerOrDirectToDispose>0</solePowerOrDirectToDispose>
<sharedPowerOrDirectToDispose>0</sharedPowerOrDirectToDispose>
</numberOfSharesPersonHas>
</item4>
<item5>
<notApplicableFlag>N</notApplicableFlag>
<classOwnership5PercentOrLess>Y</classOwnership5PercentOrLess>
</item5>
<item6>
<notApplicableFlag>Y</notApplicableFlag>
</item6>
<item7>
<notApplicableFlag>Y</notApplicableFlag>
</item7>
<item8>
<notApplicableFlag>Y</notApplicableFlag>
</item8>
<item9>
<notApplicableFlag>Y</notApplicableFlag>
</item9>
<item10>
<notApplicableFlag>N</notApplicableFlag>
<certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
</item10>
</items>
<exhibitInfo>Exhibit 99.1 Joint Filing Agreement</exhibitInfo>
<signatureInformation>
<reportingPersonName>Genextra S.p.A.</reportingPersonName>
<signatureDetails>
<signature>/s/ FRANCESCO MICHELI</signature>
<title>Francesco Micheli / Chairman and Chief Executive Officer</title>
<date>10/29/2025</date>
</signatureDetails>
</signatureInformation>
<signatureInformation>
<reportingPersonName>Francesco Micheli</reportingPersonName>
<signatureDetails>
<signature>/s/ FRANCESCO MICHELI</signature>
<title>Francesco Micheli</title>
<date>10/29/2025</date>
</signatureDetails>
</signatureInformation>
<signatureInformation>
<reportingPersonName>Matteo Bruno Renzulli</reportingPersonName>
<signatureDetails>
<signature>/s/ MATTEO BRUNO RENZULLI</signature>
<title>Matteo Bruno Renzulli</title>
<date>10/29/2025</date>
</signatureDetails>
</signatureInformation>
</formData>

</edgarSubmission>
